Genome analysis of Rossellomorea sp. y25, a deep sea bacterium isolated from the sediments of South China Sea

Bai, Shijie; Huang, Zhaosong; Li, Xue-Gong

doi:10.1016/j.margen.2024.101110

Marine Genomics

2024

DOI: 10.1016/j.margen.2024.101110

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Genome analysis of Rossellomorea sp. y25, a deep sea bacterium isolated from the sediments of South China Sea

Shijie Bai,

Zhaosong Huang,

Xue-Gong Li

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2024

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Cited by 1 publication

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The Potential of CCA-associated Bacteria to Fight Antimicrobial-Resistant Pathogens: a Genomic Survey

Lera-Lozano,

Ruiz-Toquica,

Holt

et al. 2024

Preprint

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The global rise of antimicrobial resistance has intensified efforts in bioprospecting, with researchers increasingly exploring unique marine environments for novel antimicrobials. In line with this trend, our study focused on bacteria isolated from the unique microbiome of crustose coralline algae (CCA), which has yet to be investigated for antimicrobial discovery. In the present work, bacteria were isolated from the CCA Hydrolithon boergesenii. After running antimicrobial assays against antibiotic-resistant human and marine pathogens, three isolates were selected for genome sequencing using the Oxford Nanopore technology. Genome mining of the high-quality assemblies revealed 100 putative Biosynthetic Gene Clusters (BGCs) across the three genomes. Further analysis uncovered BGCs potentially involved in the biosynthesis of novel antimicrobial compounds. Our study provides valuable resources for future research aimed at the discovery of novel antimicrobials, particularly in the face of the antibiotic-resistance global crisis and highlights the potential of specialized marine environments like CCA biofilms.

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The Potential of CCA-associated Bacteria to Fight Antimicrobial-Resistant Pathogens: a Genomic Survey

Lera-Lozano,

Ruiz-Toquica,

Holt

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

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Genome analysis of Rossellomorea sp. y25, a deep sea bacterium isolated from the sediments of South China Sea

Cited by 1 publication

References 43 publications

The Potential of CCA-associated Bacteria to Fight Antimicrobial-Resistant Pathogens: a Genomic Survey

The Potential of CCA-associated Bacteria to Fight Antimicrobial-Resistant Pathogens: a Genomic Survey

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