2023
DOI: 10.1002/aic.18230
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Genome engineering allows selective conversions of terephthalaldehyde to multiple valorized products in bacterial cells

Roman M. Dickey,
Michaela A. Jones,
Neil D. Butler
et al.

Abstract: Deconstruction of polyethylene terephthalate (PET) plastic waste generates opportunities for valorization to alternative products. We recently designed an enzymatic cascade that could produce terephthalaldehyde (TPAL) from terephthalic acid. Here, we showed that the addition of TPAL to growing cultures of Escherichia coli wild‐type strain MG1655 and an engineered strain for reduced aromatic aldehyde reduction (RARE) strain resulted in substantial reduction. We then investigated if we could mitigate this reduct… Show more

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Cited by 6 publications
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