“…Water-associated bacteria capable of biofilm formation onboard the International Space Station (ISS) have represented a challenge for the operation of the environmental control and life support system (ECLSS) ( 1 ). Bacteria isolated from the water recovery system, which recycles urine, humidity condensate, and other nonpotable water to water for crew consumption and hygiene, have been used in multiple ground studies that pertain to ECLSS biofouling ( 2 – 5 ). Similarly, isolates from the Russian SRV-K, which recovers water from humidity condensate, and the SVO-ZV, which supplies ground water delivered to the ISS, have been and continue to be investigated ( 6 ).…”