Genome-wide identification of Ran GTPase family genes from wheat (T. aestivum) and their expression profile during developmental stages and abiotic stress conditions

A necessary considering factor for breeding: growth-defense tradeoff in plants

“…Nuclear transport of immune receptors, signal transducers and transcription factors is an essential regulatory mechanism for immune activation (Gu et al 2016 ). Ras-related nuclear protein (Ran) GTPases are required for nucleocytoplasmic transport, mitotic progression, and nuclear envelope assembly in plants (Choudhury et al 2021 ; Ma et al 2007 ). A WPP domain-interacting proteins (AtWIP) were identified as plant specific KASH proteins, while Ran GTPase activating protein 1 (RanGAP1) is also a member of the WPP domain-containing protein family (Jeong et al 2005 ), which is associated with the NE by protein–protein interactions (Xu et al 2007 ).…”

“…Overexpression of AtRan1 in Arabidopsis leads to promoted elongation growth and enhanced disease resistance against P. syringae DC3000 (Xu et al 2021 ). Under biotic and abiotic stresses, TaRAN1 expression was largely unaltered, while TaRAN2 showed stress specific response (Choudhury et al 2021 ). In addition, upon activation by immunoreceptors, NE protein constitutive expresser of PR genes 5 (CPR5) undergoes an oligomer to monomer, and releases cyclin-dependent kinase inhibitor (CKI) for ETI signaling and reconfigures the selective barrier to allow significant influx of nuclear signaling cargos through NPC (Gu et al 2016 ; Wang et al 2014a ).…”