Genomic characterization of multidrug‐resistant ESBL‐producing Escherichia coli ST58 causing fatal colibacillosis in critically endangered Brazilian merganser ( Mergus octosetaceus )

Abstract

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

First Report of a Multidrug-Resistant ST58 Escherichia coli Harboring Extended-Spectrum Beta-Lactamase of the CTX-M-1 Class in a Fecal Sample of a Captive Baird's Tapir (Tapirus bairdii) in Costa Rica, Central America

“…17,37 ST58 has been reported as one of the main ESBL-producing E. coli circulating at the human-animalenvironment 38 ; however, there are very few reports of ST58 in wildlife. 10 ST58 was previously reported in a fatal case of a captive critically endangered Brazilian merganser (Mergus octosetaceus) in several organs 34 and in peri-urban South American coatis (Nasua nasua) in Brazil. 38 IncN has been associated with disseminating several bla CTX-M variants, such as bla CTX-M-1 , bla CTX-M-3 , bla CTX-M-15 , bla CTX-M-32 , bla CTX-M-40 , and bla CTX-M-65.…”

“…Food manipulation, runoff, disinfectant use, and frequent antibiotic therapy are suggested to be the main drivers for resistant bacteria transmission (i.e., mainly through horizontal gene transfer mechanisms) in these facilities. 29,31,34 Similar to human and veterinarian medicine, the most detected type of ESBL in wild animals corresponds to the 10,12,16,17 In addition to the bla CTX-M gene-family also the bla SHV-12 and bla TEM-52 were identified. 10 The most commonly reported non-ESBL phenotypes showed resistance to ampicillin, streptomycin, and tetracycline.…”

Genomic features and antimicrobial resistance patterns of Shiga toxin‐producing Escherichia coli strains isolated from food in Chile

“…Asian, European, North American and South American countries (Bai et al, 2015(Bai et al, , 2018González-Escalona & Kase, 2019;Fuentes-Castillo et al, 2020;de Carvalho et al, 2020). Furthermore, phylogenomic analysis clustered STEC strains isolated from cattle in Chile and China in the same clade.…”

“…Additionally, and although most STs belonged to the pandemic CC155, the other identified STs and CCs have been associated with illness in humans (González‐Escalona & Kase, 2019). Specifically, the ST58, predicted for STEC strains A‐10–A‐12 isolated from ground beef, has been described globally from a wide range of sources, including humans, food, livestock and wildlife, from Asian, European, North American and South American countries (Bai et al., 2015, 2018; González‐Escalona & Kase, 2019; Fuentes‐Castillo et al., 2020; de Carvalho et al., 2020). Furthermore, phylogenomic analysis clustered STEC strains isolated from cattle in Chile and China in the same clade.…”

Genomic Epidemiology of Shiga Toxin-Producing Escherichia coli Isolated from the Livestock-Food-Human Interface in South America

“…ST11 (CC11), ST58 (155), and ST297 were the most frequently detected. Those STs were isolated worldwide from human and non-human hosts, and are associated with illness both in humans and animals [47,87]. While ST11 is the main clone identified from human infections in Argentina, Brazil, Uruguay, and Paraguay; lineages of CC29 (ST16 and ST21) have emerged in human infections in Argentina, Ecuador, Brazil, Uruguay, and Chile; the latter being further identified in cattle [21,39,[52][53][54][55].…”