Genomic full‐length sequence of the <i>HLA‐B*44:348</i> allele was identified by next generation sequencing

Loginova, Maria; Smirnova, Daria; Druzhinina, Svetlana; Парамонов, И. В.

doi:10.1111/tan.14615

Cited by 5 publications

(3 citation statements)

References 3 publications

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“…and to explore the genomic landscape of complex diseases such as endometriosis [ 23 ] and thyroid cancer (Iqbal et al, 2022), as well as detect novel alleles of polymorphic gene clusters [ 24 , 25 ].…”

Section: Resultsmentioning

confidence: 99%

Advances in Molecular and Genetic Technologies and the Problems Related to Their Application in Personalized Medicine

Nakhod,

Krivenko,

Butkova

et al. 2024

JPM

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Advances in the global personalized medicine market are directly related to innovations and developments in molecular and genetic technologies. This review focuses on the key trends in the development of these technologies in the healthcare sector. The existing global developments having an impact on the evolution of the personalized medicine market are reviewed. Efficient measures to support the development of molecular and genetic technologies are proposed.

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Section: Resultsmentioning

confidence: 99%

Advances in Molecular and Genetic Technologies and the Problems Related to Their Application in Personalized Medicine

Nakhod,

Krivenko,

Butkova

et al. 2024

JPM

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show abstract

“…(49) Frontiers in Medicine | www.frontiersin.org technology still gains favor in genome-wide association studies (GWAS) for the sake of economy, and there is a gaining momentum to combine DNA microarray and NGS/TGS in genotyping toward increased resolution of population-specific haplotypes and imputation strength (82). Genomic sequencing technologies have been applied to characterize many genetic disorders (such as highly identical segmental duplications that account for over 5% of the human genome and are enriched in the short arm of the chromosome 16 (83) and diseases associated with BRCA1/2 mutations (84)), identify intratypic sequence variations [such as that of SARS-CoV-2 variants (85) and bovine papillomaviruses (86)], interrogate the genomic landscape of complex diseases [such as endometrial cancers (87) and thyroid carcinomas (88)], and discover novel alleles of polymorphic gene clusters in the human genome [such as that of the HLA system (89,90)].…”

Section: Parismentioning

confidence: 99%

“…Genomic sequencing technologies have been applied to characterize many genetic disorders (such as highly identical segmental duplications that account for over 5% of the human genome and are enriched in the short arm of the chromosome 16 ( 83 ) and diseases associated with BRCA1/2 mutations ( 84 )), identify intratypic sequence variations [such as that of SARS-CoV-2 variants ( 85 ) and bovine papillomaviruses ( 86 )], interrogate the genomic landscape of complex diseases [such as endometrial cancers ( 87 ) and thyroid carcinomas ( 88 )], and discover novel alleles of polymorphic gene clusters in the human genome [such as that of the HLA system ( 89 , 90 )].…”

Section: Technology-based Omicsmentioning

confidence: 99%

Advances and Trends in Omics Technology Development

2022

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The human history has witnessed the rapid development of technologies such as high-throughput sequencing and mass spectrometry that led to the concept of “omics” and methodological advancement in systematically interrogating a cellular system. Yet, the ever-growing types of molecules and regulatory mechanisms being discovered have been persistently transforming our understandings on the cellular machinery. This renders cell omics seemingly, like the universe, expand with no limit and our goal toward the complete harness of the cellular system merely impossible. Therefore, it is imperative to review what has been done and is being done to predict what can be done toward the translation of omics information to disease control with minimal cell perturbation. With a focus on the “four big omics,” i.e., genomics, transcriptomics, proteomics, metabolomics, we delineate hierarchies of these omics together with their epiomics and interactomics, and review technologies developed for interrogation. We predict, among others, redoxomics as an emerging omics layer that views cell decision toward the physiological or pathological state as a fine-tuned redox balance.

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Nomenclature for factors of the HLA system, update July, August and September 2022

Marsh

2023

Human Immunology

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Genomic full‐length sequence of the HLA‐B44:348* allele was identified by next generation sequencing

Abstract: Genomic full‐length sequence of the HLA‐B*44:348 allele was identified by next generation sequencing in a Russian individual.

Cited by 5 publications

References 3 publications

Advances in Molecular and Genetic Technologies and the Problems Related to Their Application in Personalized Medicine

Advances in Molecular and Genetic Technologies and the Problems Related to Their Application in Personalized Medicine

Advances and Trends in Omics Technology Development

Nomenclature for factors of the HLA system, update July, August and September 2022

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