2023
DOI: 10.21203/rs.3.rs-3134346/v1
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Genomics of Plasmodium vivax in Colombia: evidence of local bottle-necking and inter-country connectivity in the Americas

Abstract: Colombia aims to eliminate malaria by 2030 but remains one of the highest burden countries in the Americas. Plasmodium vivax contributes half of all malaria cases, with its control challenged by relapsing parasitaemia, drug resistance and cross-border spread. Using 64 Colombian P. vivax genomes collected between 2013 and 2017, we explored diversity and selection in two major foci of transmission: Chocó and Córdoba. Open-access data from other countries were used for comparative assessment of drug resistance ca… Show more

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