Genotoxic and Antimutagenic Activity of Ficus carica Extracts

Yasmeen, Nusrath; kiranmai, Gondrala Usha; Sameer, Aga Syed

doi:10.1007/978-3-031-16493-4_26

Cited by 2 publications

(1 citation statement)

References 71 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A separate study also stated in their review that riboflavin, carotenoids and triterpenes in F. carica extract are responsible for its antioxidant property by preventing oxygen reactive, which prevents cellular component damage such as DNA, proteins, and lipids from being damaged [37].…”

Section: Tvn (Total Volatile Nitrogen)mentioning

confidence: 99%

The Effects of Alcoholic Extract of Ficus carica Leaves on Some Chemical and Microbiological Properties of Beef during Refrigerated Storage

Haider,

Rafi,

Hussein

et al. 2023

Iraqi Journal of Science

View full text Add to dashboard Cite

This study explored the preservative effects of the alcoholic leaves’ extract of Ficus carica plant on beef refrigerated for 15 days. Phytochemical analysis showed that the plant extract contained terpenoids, flavonoids, tannins, saponins, and alkaloids. Furthermore, the alcoholic extract of plants significantly reduced the total viable counts of psychrotrophic bacteria, pathogenic bacteria (Proteus, Salmonella typhimiurum, Escherichia coli, and Staphylococcus aureus), and yeasts (Candida kruse, Candida lambica, and Zygosaccharomyces) isolated from meat samples, particularly at 100 and 200 mg/ml concentrations. The antioxidant activity of the extract was determined by using TBA and TVN values. The results showed that meat samples treated with 100 and 200 mg/ml of the alcoholic extract of F. carica had significantly lower TBA values (25, 0.24 mg/kg respectively) on day 5 which became 0.92, 0.53 mg/kg on day 15. Whereas the control values increased from 0.25 to 1.75 mg/kg on day 15,f ollowed by the TVN values of treatment meat samples with 100 and 200 mg/ml 5.57, 5.12 mg N/100 g meat respectively on day 5 which became 12.16, 10.65 mg N/ 100 g meat on day 15, while the TVN in control samples increased significantly (p < 0.05) from 7.35 to 15.76 mg N/100 g meat. All results confirmed that the alcoholic extract of F. carica, which is rich in bioactive compounds is more effective as a natural antibacterial, antifungal and antioxidant, than synthetic antioxidants that maintain the quality of beef, compared to the control by reducing lipid oxidation and microbial growth at refrigeration temperatures, especially at 100 and 200 mg/ml concentrations of the plant extract.

show abstract

Section: Tvn (Total Volatile Nitrogen)mentioning

confidence: 99%

The Effects of Alcoholic Extract of Ficus carica Leaves on Some Chemical and Microbiological Properties of Beef during Refrigerated Storage

Haider,

Rafi,

Hussein

et al. 2023

Iraqi Journal of Science

View full text Add to dashboard Cite

show abstract

The Potential Roles of Ficus carica Extract in the Management of COVID-19 Viral Infections: A Computer-aided Drug Design Study

Hamed,

Khalifa,

El Hassab

et al. 2024

CAD

View full text Add to dashboard Cite

Introduction: The conventional processes of drug discovery are too expensive, time-consuming and the success rate is limited. Searching for alternatives that have evident safety and potential efficacy could save money, time and improve the current therapeutic regimen outcomes. Method: Clinical phytotherapy implies the use of extracts of natural origin for prophylaxis, treatment, or management of human disorders. In this work, the potential role of common Fig (Ficus carica) in the management of COVID-19 infections has been explored. The antiviral effects of Cyanidin-3-rhamnoglucoside which is abundant in common Figs have been illustrated on COVID-19 targets. The immunomodulatory effect and the ability to ameliorate the cytokine storm associated with coronavirus infections have also been highlighted. This work involves various computational studies to investigate the potential roles of common figs in the management of COVID-19 viral infections. Results: Two molecular docking studies of all active ingredients in common Figs were conducted starting with MOE to provide initial insights, followed by Autodock Vina for further confirmation of the results of the top five compounds with the best docking score. Conclusion: Finally, Molecular dynamic simulation alongside MMPBSA calculations were conducted using GROMACS to endorse and validate the entire work.

show abstract

Genotoxic and Antimutagenic Activity of Ficus carica Extracts

Cited by 2 publications

References 71 publications

The Effects of Alcoholic Extract of Ficus carica Leaves on Some Chemical and Microbiological Properties of Beef during Refrigerated Storage

The Effects of Alcoholic Extract of Ficus carica Leaves on Some Chemical and Microbiological Properties of Beef during Refrigerated Storage

The Potential Roles of Ficus carica Extract in the Management of COVID-19 Viral Infections: A Computer-aided Drug Design Study

Contact Info

Product

Resources

About