Genotoxicity assay of landfill leachates

Beg, M. U.; Al‐Muzaini, Saleh

doi:10.1002/(sici)1098-2256(1998)13:2<127::aid-tox3>3.0.co;2-9

Cited by 7 publications

(1 citation statement)

References 12 publications

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“…The range of concentrations of cadmium, calcium, iron, lead, manganese, nickel, vanadium, and zinc were from 0.002 to 0.159, from 0.648 to 3.080, from 0.370 to 8.550, from 0.200 to 0.301, from 0.093 to 7.000, from 0.002 to 0.322, from 0.059 to 2.942, and from 0.042 to 0.469 mg/L, respectively. [13] The treatment of landfill leachate is recommended to reduce the effect on sub-surface water and ground water quality. Tables 3 and 4 revealed the presence of both conventional and heavy metals.…”

Section: Leachate Characterization At Al-sulaibiyah Landfill Sitementioning

confidence: 99%

A Comparison of Leachate Treatment Between Rhode Island and Kuwait

Al‐Muzaini

Thiem

2004

Journal of Environmental Science and Health, Part A

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The main objectives of this article were to present data on the characteristics of landfill leachate of Rhode Island Central landfill and those of Kuwait's Sulaibya landfill site, and to compare different experimental pilot plant studies for the treatment of sanitary landfill leachate, which was generally characterized by high concentration of heavy metals. The data obtained on the chemical analysis of leachate generated from two landfills in Rhode Island and Kuwait, identified variations in leachate quality due to landfill composition. Pilot Plant studies using physical/chemical and biological treatments (i.e., rotating biological contractor) were used to examine the treatment efficiency.

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Section: Leachate Characterization At Al-sulaibiyah Landfill Sitementioning

confidence: 99%

A Comparison of Leachate Treatment Between Rhode Island and Kuwait

Al‐Muzaini

Thiem

2004

Journal of Environmental Science and Health, Part A

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DNA damage induced in human peripheral blood lymphocytes by industrial solid waste and municipal sludge leachates

Bakare

Pandey

Bajpayee

et al. 2006

Environ and Mol Mutagen

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Exposure of humans to toxic compounds occurs mostly in the form of complex mixtures. Leachates, consisting of mixtures of many chemicals, are a potential risk to human health. In the present study, leachates of solid wastes from a polyfiber factory (PFL), an aeronautical plant (AEL), and a municipal sludge leachate (MSL) were assessed for their ability to induce DNA damage in human peripheral blood lymphocytes using the alkaline Comet assay. The leachates also were examined for their physical and chemical properties. Lymphocytes were incubated with 0.5-15.0% concentrations (pH range 7.1-7.4) of the test leachates for 3 hr at 37 degrees C, and treatment with 1 mM ethyl methanesulfonate served as a positive control. All three leachates induced significant (P < 0.05), concentration-dependent increases in DNA damage compared with the negative control, as measured by increases in Olive tail moment (arbitrary units), tail DNA (%), and tail length (mum). A comparison of these variables among the treatment groups indicated that the MSL induced the most DNA damage. Inductively coupled plasma emission spectrometry analysis of the leachates indicated that they contained high concentrations of heavy metals, viz. iron, manganese, nickel, zinc, cadmium, chromium, and lead. The individual, synergistic, or antagonistic effects of these chemicals in the leachates may be responsible for the DNA damage. Our data indicate that the ever-increasing amounts of leachates from waste landfill sites have the potential to induce DNA damage and suggest that the exposure of human populations to these leachates may lead to adverse health effects.

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Determining toxicity of leachates from Florida municipal solid waste landfills using a battery‐of‐tests approach

Ward

Bitton

Townsend

et al. 2002

Environmental Toxicology

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The toxicity and physicochemical parameters of municipal solid-waste (MSW) landfill leachates from six sites in north and north-central Florida, United States, were determined. Landfill leachates are complex mixtures of organic and inorganic constituents. Leachate toxicity was assayed using the acute C. dubia (48-h) and Microtoxtrade mark (15-min) assays and the chronic S. capricornutum (96-h) assay. The landfill leachates were shown to be highly toxic to both C. dubia and S. capricornutum with an EC(50) < 10% and < 15%, respectively. However, Microtoxtrade mark was not as sensitive to the leachates. Based on these results, the assays were ranked for their sensitivities to the landfill leachates; C. dubia > S. capricornutum > Microtoxtrade mark. Chemical analyses showed high concentrations of un-ionized ammonia and salts in the landfill leachates but low concentrations of heavy metals. The toxicity of the landfill leachates varied between the sites sampled and within each of the landfill sites. A significant relationship was found between the total ammonia content of the leachates and toxicity as determined by the C. dubia and S. capricornutum assays. Although the chemical constituents in Florida MSW landfill leachates may be more dilute, the toxicity of the leachates is equivalent to that from industrial waste landfills.

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Genotoxicity assay of landfill leachates

Cited by 7 publications

References 12 publications

A Comparison of Leachate Treatment Between Rhode Island and Kuwait

A Comparison of Leachate Treatment Between Rhode Island and Kuwait

DNA damage induced in human peripheral blood lymphocytes by industrial solid waste and municipal sludge leachates

Determining toxicity of leachates from Florida municipal solid waste landfills using a battery‐of‐tests approach

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