Genotoxicity testing of quizalofop-P-ethyl herbicide using the <i>Allium cepa</i> anaphase-telophase chromosome aberration assay

Yıldız, Mustafa; Arikan, Evrim Suna

doi:10.1080/00087114.2008.10589608

Cited by 89 publications

(29 citation statements)

References 39 publications

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“…The A. cepa assay is an efficient test for chemical screening and in situ monitoring of the genotoxicity effect of environmental contaminants (Fiskesjö, 1985(Fiskesjö, , 1993Barbérico et al, 2009;Siddiqui et al, 2011;Nunes et al, 2011). This test has been widely used to study the toxicity and genotoxicity of many dangerous contaminants, such as pesticides, azo dyes, food preservatives and hydrocarbons (Riffat and Ahmad, 2006;Mittergger et al, 2007;Feretti et al, 2007;Türkoğlu, 2007;Leme and Marin-Morales, 2008;Mustafa and Arikan, 2008;Ashraf and Husain, 2010), where all tests have shown that A. cepa is more sensitive for detecting toxicity and genotoxicity than other tests. Studies conducted with real effluents obtained from a textile mill revealed that water contaminated with azo dyes induces chromosomal and nuclear aberrations in A. cepa (Caritá and Marin, 2008;Leme and Marin-Morales, 2009).…”

Section: Introductionmentioning

confidence: 99%

Genotoxicity and toxicity evaluations of ECF cellulose bleaching effluents using the Allium cepa L. Test

Venegas

2012

Braz. J. Biol.

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Toxicity and genotoxicity tests were performed on root cells of Allium cepa in order to evaluate wastewater quality following an ECF cellulose bleaching process. The results revealed a toxic effect of the effluent, with inhibition of meristem growth and generally lower values of metaphase, anaphase and telophase indices at pH 10.5 than pH 7 for all effluent concentrations. The genotoxicity effect was different from the toxic effect given that the micronucleus and the chromosomal aberration tests in anaphase-telophase cells were low over all ranges of the studied effluent concentrations.Keywords: Allium cepa, toxicity, genotoxicity, ECF bleaching effluent, Kraft cellulose.Genotoxicidade e toxicidade em Allium cepa L.: avaliação da qualidade do efluente no processo de branqueamento da celulose ResumoOs testes de toxicidade e genotoxicidade foram realizados em células da raiz de Allium cepa, a fim de avaliar a qualidade do efluente na sequência de um processo de branqueamento de celulose ECF. Os resultados revelaram um efeito tóxico do efluente, com inibição de crescimento do meristema e valores geralmente baixos de metáfase, anáfase e índices de telófase, a pH 10,5 e pH 7, para todas as concentrações do efluente. O efeito de genotoxicidade foi diferente do efeito tóxico, uma vez que o micronúcleo e os testes de aberrações cromossômicas em anáfase-telófase das células foram baixos em todas as gamas de concentrações do efluente estudado.Palavras-chave: Allium cepa, toxicidade, genotoxicidade, branqueamento por sequências ECF, Kraft celulose.

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Section: Introductionmentioning

confidence: 99%

Genotoxicity and toxicity evaluations of ECF cellulose bleaching effluents using the Allium cepa L. Test

Venegas

2012

Braz. J. Biol.

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“…Reduction of RGR in Lemna gibba, L. minor and Allium cepa has been reported by increasing the concentrations of some herbicides such as Propanil and Quizalofop-p-ethyl in the previous studies [11,23,29]. Possibly, indirect decrease or inhibition of photosynthesis by GS could be one of the important reasons for the delayed growth [11].…”

Section: Discussionmentioning

confidence: 99%

Toxicological Effects of a Post Emergent Herbicide on Spirodela polyrhiza as a Model Macrophyte: A Comparison of the Effects of Pure and Nano-capsulated Form of the Herbicide

Torbati

Mahmoudian

Alimirzaei

2018

IJT

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Background: One of the main reasons of environmental contaminations is the broad application of herbicides. Controlled release technologies such as encapsulation of herbicides are as an effective tool to reduce environmental contaminations. The aim of the present study was successful nanocapsulation of Gallant Super (GS), its characterization and compare the physiological responses of Spirodela polyrhiza L. upon exposure to GS and its encapsulated form.Methods: Nanocapsulation of GS in the poly (methyl methacrylate) (PMMA) was performed in the Department of Nanotechnology, Faculty of Sciences and biological effects of the contaminants on S. polyrhiza was investigated in Biotechnology Research Center, both in Urmia University, Urmia, Iran in 2016. The surface morphology of PMMA/GS nanocapsules was studied by SEM and TEM and their chemical characterization was determined by FT-IR spectroscopy. For assessment of the effects of the encapsulated Gallant Super (ECGS) and GS on S. polyrhiza, some plant physiological parameters were investigated.Results: Direct treatment of GS had more and notable negative effects on the plant growth when compared with ECGS treatments. Moreover, different examined concentrations of the two contaminant groups led to the remarkable induction of the activities of the antioxidant enzymes such as SOD. Even though the enhancement of the antioxidant enzymes activities when the plant was treated with GS was notably more than the effects of ECGS.Conclusion: ECGS caused to the fewer changes in the plant physiological parameters and negative effects of the treatment of ECGs were less than when the plant had direct contact with GS.

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“…Levan (1938) described colchicine mitosis (c-metaphase or c-anaphase) as an inactivation of the spindle followed by a random scattering of the condensed chromosomes in the cell. According to Mustafa & Arikan (2008), a large number of laggard chromosomes and c-anaphases indicate that a test compound acted as a potent spindle inhibitor. The induction of vagrant chromosomes according to Elghamery et al (2003), leads to the separation of unequal number of chromosomes in the daughter nuclei and subsequently formation of daughter cells with unequal sized or irregularly shaped nuclei at interphase.…”

Section: Examination Of the Results Of Tests With Camellia Sinensis Inmentioning

confidence: 99%

Modulation of Mutagen-Induced Genotoxicity by two Lesotho Medicinal Plants in Allium cepa L

Asita¹,

Heisi²,

Tjale³

2015

ENRR

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Methanolic extracts (mg mL -1 ) of Dicoma anomala (0.0625, 0.125, 0.25), Chenopodium album (0.078, 0.156, 0.313), used in traditional medicine in Lesotho, and Camellia sinensis (0.1094, 0.2085, 0.44) were assessed for cytotoxicity, genotoxicity and modulation of Cyclophosphamide (CP 1.25 mg mL -1 ) -and EMS (0.25 mg mL -1 )-induced genotoxicity using the Allium cepa assay following 24 hours treatment. Cytotoxicity was measured by the mitotic index (MI). Genotoxicity (GT) was expressed as the number of aberrant mitotic cells per 100 mitotic cells. The MI and GT of test groups (triplicates), were compared with the negative (water) control group using t-test. Modulatory effect (ME) was calculated as, ME(%) = (1-(A-B)/(A-C) × 100) -1. A positive ME indicated an increase (synergism or potentiation) while a negative ME indicated a reduction (anti-genotoxicity) of mutagen-induced genotoxicity. The concentrations of D. anomala extract were cytotoxic and genotoxic. Mixtures of CP or EMS with the lower concentrations of D. anomala extract were more genotoxic than CP (250.50% increase) or EMS (149.74 and 157.37 % increase) or extracts alone. Only 0.313 mg mL -1 of C. album extract was cytotoxic but none of the three concentrations was genotoxic. Mixtures of CP with extracts of C.album were cytotoxic. CP-induced genotoxicity was reduced (55.18, 68.36, 57.40 %) and EMS-induced genotoxicity was also reduced by low concentrations (50.72, 61.13 %) of C.album extract. However, 0.313 mg mL -1 C. album extract increased (236.75%) EMS-induced genotoxicity. C. sinensis extracts and their mixtures with CP were not cytotoxic or genotoxic. CP-induced genotoxicity was reduced (63.61, 66.62, 78.64 %) but EMS-induced genotoxicity was increased (124.97, 4.48, 110.52 %) by C. sinensis extract.

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Genotoxicity testing of quizalofop-P-ethyl herbicide using the Allium cepa anaphase-telophase chromosome aberration assay

Cited by 89 publications

References 39 publications

Genotoxicity and toxicity evaluations of ECF cellulose bleaching effluents using the Allium cepa L. Test

Genotoxicity and toxicity evaluations of ECF cellulose bleaching effluents using the Allium cepa L. Test

Toxicological Effects of a Post Emergent Herbicide on Spirodela polyrhiza as a Model Macrophyte: A Comparison of the Effects of Pure and Nano-capsulated Form of the Herbicide

Modulation of Mutagen-Induced Genotoxicity by two Lesotho Medicinal Plants in Allium cepa L

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