2023
DOI: 10.1186/s13104-023-06483-z
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Genotype variation of ACE and ACE2 genes affects the severity of COVID-19 patients

Ingrid Faustine,
Deli Marteka,
Amarila Malik
et al.

Abstract: Objective Genetic polymorphisms in ACE and ACE2 genes are involved in the RAS regulation of blood pressure and their activity may confer susceptibility to hypertension. In addition, they may play a role in SARS-CoV-2 pathogenesis and the severity of COVID-19. This study aims to determine the effect of genetic variations in the ACE (rs4331) and ACE2 (rs2074192) genes with hypertension comorbidity on the severity of COVID-19 in the Indonesian population. Result … Show more

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