Genotypic distribution of rotavirus strains causing severe gastroenteritis in Gyeonggi province, South Korea, from 2003 to 2005

Huh, Jeong Weon; Kim, Woon Ho; Yoon, Mi‐Hye; Lim, Young Hee

doi:10.1007/s00705-008-0275-7

Cited by 20 publications

(13 citation statements)

References 23 publications

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“…Study data from the current investigation indicated that the G4P[6] was the most prevalent serotype again, replacing the G1P[8] strain, which was dominant in the previous Seoul survey; its G/P combinations accounted for 78.9% among all combinations. This finding was in agreement with previous studies conducted in other countries and worldwide in which G4P [6] was also the most prevalent [Banyai et al, 2004Kang et al, 2005;Huh et al, 2009]. In general, G4P[6] is considered a rare combination, but P[6] strains combined with G1, G2, G3, or G4 have been reported as a cause of outbreaks of nosocomial infections in hospitals and newborn nurseries [Jagannath et al, 2000;Lee et al, 2001;Linhares et al, 2002;Rahman et al, 2003].…”

Section: Discussionsupporting

confidence: 92%

“…A similar trend has been reported in the recent Korean studies which uncovered a temporal change in the most common G/P type combinations of rotaviruses that is dependent on season and geography. The G1P[8] (25.4%) strain was the most prevalent genotype until 1997 [Seo and Sim, 2000], after which the predominant type shifted to G4P[8] (7.8%) [Song et al, 2003], then to G2P[4] (45.7-52.4%) [Min et al, 2004;Moon et al, 2007], then to G4P[6] (18.9-27%) Huh and Kim, 2009], and then to G1P[8] (25.4%) [Le et al, 2008]. Study data from the current investigation indicated that the G4P[6] was the most prevalent serotype again, replacing the G1P[8] strain, which was dominant in the previous Seoul survey; its G/P combinations accounted for 78.9% among all combinations.…”

Section: Discussionmentioning

confidence: 99%

“…Surveillance studies have revealed significantly different changes in rotavirus types during recent years. The G2, G3, G4, and G9 strains were most frequent between 1998 and 2004 [Song et al, 2003;Min et al, 2004;Kim et al, 2005;Moon et al, 2007;Lee et al, 2008;Huh and Kim, 2009], while epidemiologic reports spanning 1987-1999 indicated that G1-G4 were most common, with G1 being the predominant strain [Kim, 1993;Kim et al, 1999;Seo and Sim, 2000]. Our recent data conducted in Seoul indicated that the G1 strain has become the most common serotype [Le et al, 2008].…”

Section: Introductionmentioning

confidence: 92%

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Genetic variation of G4P[6] rotaviruses: Evidence for novel strains circulating between the hospital and community

Shim

Jung

et al. 2010

Journal of Medical Virology

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One hundred forty-six fecal specimens collected between 2007 and 2008 from infants with acute gastroenteritis were screened for rotavirus by ELISA with VP6-specific antibody. One hundred twenty-three of the samples (84.2%) were confirmed to be positive for group A rotavirus (community-acquired, n = 90 [73.2%] and nosocomial, n = 33 [26.8%]), and were typed subsequently using RT-PCR and sequence analysis methods. Determination of G- and P-type combinations showed that G4P[6] (78.9%) was the most common strain, followed by G3P[8] (7.3%), G1P[8] (6.5%), G2P[4] (0.8%), G2P[6] (0.8%), G1P[6] (0.8%), and G9P[8] (0.8%) strains. Of the 97 G4P[6] strains, 62 (63.8%) were responsible for community-acquired cases and 35 (36.1%) were hospital-acquired cases. Phylogenetic analysis of the VP7 gene from the G4P[6] strains revealed that both the community-acquired and nosocomial strains were segregated to the human rotaviruses circulating world-wide, including the prototype vaccinal strain, ST3, which constituted a novel sublineage in lineage 1. Owing to the recent emergence of G4P[6] rotaviruses within the hospital, as well as in the community, the findings from this study are important since they provide new information concerning the community and nosocomial spread of rotaviruses.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 92%

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Genetic variation of G4P[6] rotaviruses: Evidence for novel strains circulating between the hospital and community

Shim

Jung

et al. 2010

Journal of Medical Virology

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“…Furthermore, unusual G and P combination genotypes, including G3P[3], G3P[9], G3P[10], G8P[8], G11P[4], G11P[25], and G12P[6], have been isolated from South Korea [25]. From 2003 to 2005, the G3 genotypes were predominant [26]. Although the P[9] genotype has been detected in some rotavirus surveillance studies in South Korea, no significant emergence of P[9] genotypes has been observed in the Korean population [22]; however, no studies have specifically focused on this genotype.…”

Section: Introductionmentioning

confidence: 99%

Whole-Genome Analysis of a Rare Human Korean G3P[9] Rotavirus Strain Suggests a Complex Evolutionary Origin Potentially Involving Reassortment Events between Feline and Bovine Rotaviruses

et al. 2014

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A rare human rotavirus, G3P[9] strain RVA/Human-tc/KOR/CAU12-2-51/2013/G3P[9], was isolated from the stool of a 9-year-old female hospitalized with acute watery diarrhea in August 2012 in South Korea using a cell culture system, and its genome was analyzed. The complete genomic constellation of the CAU12-2-51 strain revealed a novel genotype constellation for human rotavirus, G3-P[9]-I2-R2-C2-M2-A3-N2-T3-E3-H3. Phylogenetic analysis revealed that the CAU12-2-51 strain originated from feline- and bovine-like reassortment strains. The genes encoding VP4, VP7, NSP1, NSP3, NSP4, and NSP5 were related to human/feline-like and feline rotavirus strains, whereas the remaining five genes encoding VP1, VP2, VP3, VP6, and NSP2 were related to the human/bovine-like and bovine rotavirus strains. This novel strain was identified for the first time, providing evidence of feline/bovine-to-human transmission of rotavirus. The data presented herein provide information regarding rotavirus diversity and evolution.

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“…In South Korea, data from 1980 to 1999 showed that rotavirus accounted for 46% of 4,668 Korean children admitted to hospital with gastroenteritis [Seo and Sim, 2000]. However, data since 2003 has shown lower rotavirus‐positive rates of 19% (1,367/7,060) for 2003–2005 from Gyeonggi province hospitals [Huh et al, 2009], 18% (571/3,174) for 2004–2005 from Seoul metropolitan hospitals [Lee et al, 2008], and 22% (1,337/6,057) for 2005–2007 from eight major hospitals in Nationwide [Lee et al, 2009]. It is probably the improvement of income levels, and thought might be related to improved sanitation.…”

Section: Discussionmentioning

confidence: 99%

Full genomic analysis of a human rotavirus G1P[8] strain isolated in South Korea

Cho

Jheong

Lee

et al. 2012

Journal of Medical Virology

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A rotavirus G1P[8] strain C1-81 was isolated from a 5-month-old female infant admitted to hospital with fever and severe diarrhea in Incheon, South Korea. To investigate its full genomic relatedness and its group, the full genome of strain C1-81 was determined. Based on a full genome classification system, C1-81 was shown to possess the typical Wa-like genotype constellation: G1-P[8]-I1-R1-C1-M1-A1-N1-T1-E1-H1. On the basis of sequence similarities, the strain was shown to be the closest related strain to contemporary human rotavirus strains with recent strains isolated in Asia. This C1-81 strain showed the highest degree of nucleic acid similarity (98.8% and 97%) to G1 B4633-03 and P[8] (Thai-1604 and Dhaka8-02), respectively. This is the first report that group A rotavirus was analyzed with G1P[8] in South Korea. The study of the complete genome of the virus will help understanding of the evolution of rotavirus.

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Genotypic distribution of rotavirus strains causing severe gastroenteritis in Gyeonggi province, South Korea, from 2003 to 2005

Cited by 20 publications

References 23 publications

Genetic variation of G4P[6] rotaviruses: Evidence for novel strains circulating between the hospital and community

Genetic variation of G4P[6] rotaviruses: Evidence for novel strains circulating between the hospital and community

Whole-Genome Analysis of a Rare Human Korean G3P[9] Rotavirus Strain Suggests a Complex Evolutionary Origin Potentially Involving Reassortment Events between Feline and Bovine Rotaviruses

Full genomic analysis of a human rotavirus G1P[8] strain isolated in South Korea

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