Genotyping of Human Papilloma Virus (HPV) in female condyloma acuminata patient in Dr. Soetomo Hospital, Surabaya

Abstract

Human Papilloma Virus (HPV) cause the most common sexually transmitted infection in women. HPV may lead to clinical manifestation as condyloma acuminata. The type of HPV are divided into two categories: low risk and high risk. Objective: To determine the type of HPV in female condyloma acuminata patient. Material and methods: A cross sectional study was conducted in Dermatology Venereology Outpatient Clinic Dr. Soetomo Hospital Surabaya from February, 2007 to May, 2007. A total of 13 female patients with condyloma acuminata were includ in this study. Nucleic acids amplification assays (Polymerase Chain Reaction) used to detect the HPV infection. Results: Condyloma acuminata mostly caused by HPV-11 (30,76%) and HPV-6 (23,07%). Only 1 patient in this study caused by HPV 18. 38% of condyloma acuminata in this study caused by multiple infection of HPV. Conclusion: Molecular assay are gold standard to identification of HPV in the condyloma acuminata patient.

Treatment of condylomata acuminata caused by low-risk human papillomavirus with chloroquine phosphate gel

“…Certain low-risk types of HPV, such as HPV6 and HPV11, are associated with condylomata acuminata (CA; anogenital warts) and other types of warts (2). In 90% of cases, the CA is caused by HPV6 and/or HPV11, and in 38% of patients, it is attributed to multiple HPV infections (3). Current treatments for CA in patients infected with low-risk HPVs primarily include self-application of imiquimod, podophyllotoxin and tea polyphenol ointment (4).…”