Hydrocarbon exploration potential of the Niger Delta, Nigeria, without doubt, contributes greatly to the economy of the nation due to its sedimentary thickness. However, the sedimentary thickness of the region has been documented but there is a paucity of information in the usage of the high-resolution aeromagnetic data to determine the sedimentary thickness of Oloibiri (OML 29) and Degema (OML 11) areas. Thus, this study was undertaken to determine the sedimentary thickness of the area using the high-resolution aeromagnetic data acquired from the Nigeria Geological Survey Agency (NGSA). Spectral depth analysis, Standard 3D Euler Deconvolution, and Source Parameter imagine (SPI) techniques were employed to estimate the sedimentary thickness of the area. A true depth of 8.41 km, 7.01 km, and 5.5 km using spectral depth analysis, Euler Deconvolution with a Structural Index (SI) of 1, and Source Parameter Imaging techniques, respectively, were revealed. These values fall within the sedimentary thickness range of the region as the data was employed. Thus, if other conditions are met, the area is plausible for hydrocarbon probing.