The Manson crater is a 36-km-diameter, well-preserved, but buried, impact structure in the United States of America. In 1991 and 1992, 12 cores were drilled in a joint Iowa Geological Survey Bureau-USGS effort. We have sampled 11 of the 12 cores, as well as the two cores drilled in 1953. About 140 samples from these drill cores were studied for their petrographical and geochemical characteristics to accumulate a database for target rocks and impact lithologies present at the Manson crater. The results provide a complete petrographical and geochemical database for impactite and target lithologies at the Manson crater. A variety of impactite lithologies are present, consisting of impact melt rocks, suevites, and several different types of breccia, including an unusual impact melt breccia that contains melt in the matrix as well as some melt clasts. The composition of the impactites can be reproduced by mixtures of the different types of target rocks present. Our results from least-square mixing calculations show that the M1 impact melt breccia has been formed from a mixture of shale, Red Clastics, a mafic component ("amphibolite"), and granite, with minor contributions from carbonate and biotite granite. The results of the calculations indicate about 19% shale, 20% Red Clastics (sandstone, siltstone), 37% amphibolite gneiss, 3% biotite gneiss, and 19% granite for the M1 impact melt breccias. The calculations for the M1 suevite did not produce mixing proportions that were as well constrained as for the M1 impact melt breccias, but about 25% shale, 9% Red Clastics, 43% amphibolite gneiss, 4% biotite gneiss, and 17% granite are the best fit. The composition of the M11 melt breccias can be reproduced by about 19% shale, 25% Red Clastics, and 48% mafic gneiss components, with some contribution (7%) from the granitic target rocks. In addition, we have studied the composition of feldspars from the M1 drill core in comparison with feldspars from the Crow Creek Member in South Dakota, which had been proposed before to be a distal impact ejecta of the Manson crater. We find slight differences between the compositions of the two feldspar populations.