The Domeyko Range (Precordillera) of northern Chile represents the western slope of the Central Andes, forming a ∼800 km long, north-south trending belt that hosts some of the largest porphyry Cu-Mo deposits of the world (Figure 1b), including the Eocene-Oligocene behemoths Chuquicamata and La Escondida deposits (Camus & Dilles, 2001; Cooke et al., 2008). This belt is formed by a core of upper Paleozoic basement rocks thrusted over Mesozoic sedimentary units formerly deposited in a long-lived depocenter known as the Domeyko Basin (Figure 1). The formation of this late Eocene-Oligocene metallogenic belt was intimately related to the inception of the Domeyko fault system (DFS) (e.g., Falla Oeste, Sierra de Varas, and Sierra Castillo faults; Figure 1), a trench-parallel structural system that controlled the intrusion of porphyries, especially at the intersection with continental-scale, oblique-to-the-trench NW-trending lineaments (J. P. Richards, 2003; Salfity, 1985). These crustal lineaments have been associated with a pre-Andean basement fabric acquired during the early Paleozoic accretional evolution (Chernicoff et al., 2002; Ramos, 1994; Salfity, 1985). Although this fabric has been intensely modified by Mesozoic-Cenozoic tectonomagmatic events, these lineaments can be inferred based on scattered NW-striking faults exposed from Coastal Cordillera to the Domeyko Range (Figure 1b), as well as volcanic alignments and faults at the Altiplano-Puna (Norini et al., 2013).