Geographic and population variation in coronary artery dimensions across Southern India: A multicentre cross sectional study

Abstract

Ischemic Heart Diseases (IHD) among Asian Indian migrants in the western world are documented with high prevalence. We aimed to assess population specific variation in artery dimensions among normal and Single Vessel Disease (SVD) patients among four states of Southern India: Telangana, Karnataka, Kerala and Tamil Nadu using Quantitative Coronary Angiography (QCA) in the disease presentations. QCA of four thousand patients of Indian origin were studied prospectively after procuring the ethical clearance. Informed consents were obtained. Post Percutaneous Coronary Angioplasty (PCI) as well as Post Coronary Bypass Operations (CABG) and patient being diabetic for ≥5 years were excluded. Principal Component Analysis (PCA) was performed with samples to identify region-specific clustering.