Geographic Characteristics of Various Cancers in Yogyakarta Province, Indonesia: A Spatial Analysis at the Community Level

Solikhah, Solikhah; Perwitasari, Dyah Aryani; Rejeki, Dwi Sarwani Sri

doi:10.31557/apjcp.2022.23.4.1231

Cited by 7 publications

(7 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This condition might not apply to the other two districts which have more extensive areas and lower population density. Remarkably, our findings differ from a very recent report by Solikhah et al (2022) that shows a very high CRC burden in the Sleman District (crude rate=332 per 100,000 population at risk). The discrete method of this study and the use of hospitalbased registries may explain its different results from ours.…”

Section: Discussioncontrasting

confidence: 99%

“…Information about cancer geographical variation in Indonesia is also very limited. One spatial study in Yogyakarta Province described the geographical variance of cancer incidence, including CRC, for cases diagnosed in 2019-2020 at the district level (Solikhah et al, 2022). This study did not describe temporal trends nor sub-district level variance and only collected data from four hospital-based registries.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Temporal and spatial analyses of colorectal cancer incidence in Yogyakarta, Indonesia: a cross-sectional study

et al. 2023

View full text Add to dashboard Cite

We aimed to explore the district-level temporal dynamics and sub-district level geographical variations of colorectal cancer (CRC) incidence in the Special Region of Yogyakarta Province. We performed a cross-sectional study using data from the Yogyakarta population-based cancer registry (PBCR) comprised of 1,593 CRC cases diagnosed in 2008-2019. The age-standardized rates (ASRs) were determined using 2014 population data. The temporal trend and geographical distribution of cases were analysed using joinpoint regression and Moran’s I statistics. During 2008-2019, CRC incidence increased by 13.44% annually. Joinpoints were identified in 2014 and 2017, which were also the periods when annual percentage change (APC) was the highest throughout the observation periods (18.84). Significant APC changes were observed in all districts, with the highest in Kota Yogyakarta (15.57). The ASR of CRC incidence per 100,000 person- years was 7.03 in Sleman, 9.20 in Kota Yogyakarta, and 7.07 in Bantul district. We found a regional variation of CRC ASR with a concentrated pattern of hotspots in the central sub-districts of the catchment areas and a significant positive spatial autocorrelation of CRC incidence rates in the province (I=0.581, p<0.001). The analysis identified four high-high clusters sub-districts in the central catchment areas. This is the first Indonesian study reported from PBCR data, showing an increased annual CRC incidence during an extensive observation period in the Yogyakarta region. A heterogeneous distribution map of CRC incidence is included. These findings may serve as basis for CRC screening implementation and healthcare services improvement.

show abstract

Section: Discussioncontrasting

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Temporal and spatial analyses of colorectal cancer incidence in Yogyakarta, Indonesia: a cross-sectional study

et al. 2023

View full text Add to dashboard Cite

show abstract

“…In particular, subdistricts of Yogyakarta City generally had a higher ASR than Bantul and Sleman. This finding contrasts the earlier study [ 18 ] showing a higher BC incidence rate in Sleman than in Yogyakarta City. Reasons for this discrepancy may be the usage of PBCR data and ASRs for calculating incidence in our study.…”

Section: Discussioncontrasting

confidence: 99%

“…However, little is understood regarding this topic in Indonesia. An earlier study had been conducted in Yogyakarta Province [ 18 ]. It described the geographical variations of BC incidence among various types of cancers at the district level in 2019–2020 using data from four hospital-based registries.…”

Section: Introductionmentioning

confidence: 99%

Breast cancer incidence in Yogyakarta, Indonesia from 2008–2019: A cross-sectional study using trend analysis and geographical information system

Puspitaningtyas

Wiranata

et al. 2023

PLoS ONE

View full text Add to dashboard Cite

Background Breast cancer is a significant public health concern worldwide, including in Indonesia. Little is known about the spatial and temporal patterns of breast cancer incidence in Indonesia. This study aimed to analyze temporal and spatial variations of breast cancer incidence in Yogyakarta Province, Indonesia. Methods The study used breast cancer case data from the Yogyakarta Population-Based Cancer Registry (PBCR) from 2008 to 2019. The catchment areas of the PBCR included the 48 subdistricts of 3 districts (Sleman, Yogyakarta City, and Bantul). Age-standardized incidence rates (ASR) were calculated for each subdistrict. Joinpoint regression was used to detect any significant changes in trends over time. Global Moran’s and Local Indicators of Spatial Association (LISA) analyses were performed to identify any spatial clusters or outliers. Results The subdistricts had a median ASR of 41.9, with a range of 15.3–70.4. The majority of cases were diagnosed at a late stage, with Yogyakarta City having the highest proportion of diagnoses at stage 4. The study observed a significant increasing trend in breast cancer incidence over the study period the fastest of which is in Yogyakarta City with an average annual percentage change of 18.77%, with Sleman having an 18.21% and Bantul having 8.94% average changes each year (p <0.05). We also found a significant positive spatial autocorrelation of breast cancer incidence rates in the province (I = 0.581, p <0.001). LISA analysis identified 11 subdistricts which were high-high clusters in the central area of Yogyakarta City and six low-low clusters in the southeast region of the catchment area in the Bantul and Sleman Districts. No spatial outliers were identified. Conclusions We found significant spatial clustering of BC ASR in the Yogyakarta Province, and there was a trend of increasing ASR across the region. These findings can inform resource allocation for public health efforts to high-risk areas and develop targeted prevention and early detection strategies. Further res is needed to understand the factors driving the observed temporal and spatial patterns of breast cancer incidence in Yogyakarta Province, Indonesia.

show abstract

“…Most breast cancer patients in Indonesia are diagnosed at > 55 years of age (Belete et al, 2022;Moradinazar et al, 2019). However, approximately 19.22% and 0.79% of cancer cases occur in patients aged 45 and 18 years, respectively (Solikhah et al, 2022). The WHO reports that between the 1980s and 2020, age-standardized breast cancer mortality decreased by 40% in high-income nations, making breast cancer survivors the most common type of cancer survivors (Belete et al, 2022).…”

Section: Introductionmentioning

confidence: 99%

Health-Related Quality of Life in Postmenopausal Women With Advanced Breast Cancer Receiving Adjuvant Hormone Therapy (Ribociclib and Letrozole)

Rohman,

Anwarudin,

Azizah

et al. 2024

View full text Add to dashboard Cite

Breast cancer is a type of cancer that affects many women in Indonesia. Adjuvant hormone therapies, such as letrozole and ribociclib, have succeeded in improving the patient's quality of life. This study aimed to assess the quality of life of postmenopausal women with advanced breast cancer who received adjuvant hormone therapy with ribociclib and letrozole. A cross-sectional study was conducted using retrospective data from postmenopausal female breast cancer patients at Dharmais Cancer Hospital between 2020 and 2023 who met the inclusion criteria. To determine the impact of sociodemographics on patient quality of life, data were examined using the quality of life score (EQ5D5L) and Spearman test. There were 29 patients, with a mean age of 54.9 years (SD = 8.65); the highest education level was high school (34.5%); The majority of occupations are housewives (69%), and the majority are stage IV (34.5%). The mean utility and VAS values of Ribociclib were 0.885 and 81.66, respectively, whereas those for letrozole were 0.725 and 78.46, respectively. Analysis of the relationship between quality of life and patient characteristics showed that the quality of life of patients with breast cancer treated with adjuvant ribociclib and letrozole therapy was influenced by the stage of breast cancer (p = 0.008). These findings indicate that patients receiving ribociclib and letrozole therapy have a good quality of life, which quality of life quality of life is influenced by the stage of malignancy. Keywords: breast cancer, quality of life, letrozole, ribociclib, post menopause

show abstract

Geographic Characteristics of Various Cancers in Yogyakarta Province, Indonesia: A Spatial Analysis at the Community Level

Cited by 7 publications

References 47 publications

Temporal and spatial analyses of colorectal cancer incidence in Yogyakarta, Indonesia: a cross-sectional study

Temporal and spatial analyses of colorectal cancer incidence in Yogyakarta, Indonesia: a cross-sectional study

Breast cancer incidence in Yogyakarta, Indonesia from 2008–2019: A cross-sectional study using trend analysis and geographical information system

Health-Related Quality of Life in Postmenopausal Women With Advanced Breast Cancer Receiving Adjuvant Hormone Therapy (Ribociclib and Letrozole)

Contact Info

Product

Resources

About