Geographical region traceability of Poria cocos and correlation between environmental factors and biomarkers based on a metabolomic approach

Liu, Xiaoliu; Zhong, Can; Formalanalysis, Jing Xie; Líu, Hao; Xie, Zhenni; Zhang, Shuihan; Jin, Jian

doi:10.1016/j.foodchem.2023.135817

Cited by 12 publications

(3 citation statements)

References 28 publications

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“…Quality control (QC) samples were prepared by pooling aliquots of all samples that were representative of the samples being probed, and were used for data normalization [33] . Blank samples (75 % ACN in water) and QC samples were injected for every six samples during acquisition.…”

Section: Quality Control and Components Identificationmentioning

confidence: 99%

Identification of Markers of Saccharides in Polygonati Rhizoma During the Steaming Process by MALDI-TOF Mass Spectrometry Imaging

LIU,

CHEN,

LAO

et al. 2024

Food Science and Human Wellness

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Polygonati rhizoma is often used in Chinese medicine and as food. In this study, atmospheric pressure matrix-assisted laser desorption ionization and ion trap time-of-flight mass spectrometry techniques were applied to Polygonati rhizoma samples from Polygonati cyrtonema species. Positive ions were mainly detected in the mass range of m/z 200-600, while negative ions were mainly observed in the mass range of m/z 100-450. A total of 263 components were identified and the spatial distribution and changes in saccharides contents during the steaming process of Polygonati rhizoma were investigated. Monosaccharide and disaccharide exhibit a relatively uniform distribution, while the oligosaccharides were mainly found in the bast of fresh Polygonati rhizoma. Although the contents of monosaccharide and disaccharide were increased during steaming, that of trisaccharide, tetrasaccharide,and pentasaccharide were decreased. We used the five saccharide types with the greatest variation in content as variables for the principal component analysis (PCA) and cluster analysis. Both PCA and cluster analysis showed that these five saccharides can be used as markers in the steaming process of the Polygonati rhizoma. Present study of mass spectrometry imaging provides novel insights into the spatiotemporal accumulation patterns of saccharides in Polygonati rhizoma, improving our understanding of the steaming process.

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Section: Quality Control and Components Identificationmentioning

confidence: 99%

Identification of Markers of Saccharides in Polygonati Rhizoma During the Steaming Process by MALDI-TOF Mass Spectrometry Imaging

LIU,

CHEN,

LAO

et al. 2024

Food Science and Human Wellness

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show abstract

“…However, when an analyte consists of unknown compounds, it is difficult to qualitatively analyze. This problem can be solved by using high-resolution mass spectrometry with nontarget screening technologies [ 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Traceability Research on Geographic Erigeron breviscapus Based on High-Resolution Mass Spectrometry and Chemometric Analysis

Zhang,

Tian,

Lin

et al. 2024

Molecules

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A method was developed to identify and trace the geographic sources of Erigeron breviscapus using high-resolution mass spectrometry and chemometrics. The representative samples were collected from the geographic area of Honghe Dengzhanhua and other areas in Yunnan province and Guizhou province. The data points could be determined well using the PCA and PLS-DA diagram. A total of 46 characteristic compounds were identified from Honghe Dengzhanhua and within Guizhou province, but 37 compounds were different from Honghe Dengzhanhua and other counties in Yunnan province. Two biomarkers were found from three regions. Their structures were inferred as 8-amino-7-oxononanoic acid and 8-hydroxyquinoline, and they had the same molecular composition. This may suggest that a possible synthesis pathway can be proven in the future.

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“…High-resolution mass spectrometry is one of the commonly used and effective traceability technologies [8][9][10][11]. In our laboratory, TOF and UPLC-PDA have also been used to trace the origins of Dendrobium devonianum and Dendrobium officinale produced in the same area; Dendrobium devonianum and Dendrobium officinale can be better distinguished through relevant PCA and VIP analyses, etc., but the number of confirmed differential markers obtained was small, and the amount of characteristic information about the differential markers was low [7,12].…”

Section: Introductionmentioning

confidence: 99%

Traceability Research on Dendrobium devonianum Based on SWATHtoMRM

Lin,

Chen,

et al. 2023

Foods

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SWATHtoMRM technology was used in this experiment to further identify and trace the sources of Dendrobium devonianum and Dendrobium officinale produced in the same area using TOF and MS-MRM. After the conversion of the R package of SWATHtoMRM, 191 MRM pairs of positive ions and 96 pairs of negative ions were obtained. Dendrobium devonianum and Dendrobium officinale can be separated very well using the PCA and PLS-DA analysis of MRM ion pairs; this shows that there are obvious differences in chemical composition between Dendrobium devonianum and Dendrobium officinale, which clearly proves that the pseudotargeted metabolomics method based on SWATHtoMRM can be used for traceability identification research. A total of 146 characteristic compounds were obtained, with 20 characteristic compounds in Dendrobium devonianum. The enrichment pathways of the characteristic compounds were mainly concentrated in lipids and atherosclerosis, chagas disease, fluid shear stress and atherosclerosis, proteoglycans in cancer, the IL-17 signaling pathway, the sphingolipid signaling pathway, diabetic cardiomyopathy, arginine and proline metabolism, etc., among which the lipid and atherosclerosis pathways were more enriched, and 11 characteristic compounds affected the expression levels of IL-1, TNFα, CD36, IL-1β, etc. These can be used as a reference for research on variety improvement and active substance accumulation in Dendrobium devonianum and Dendrobium officinale.

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Geographical region traceability of Poria cocos and correlation between environmental factors and biomarkers based on a metabolomic approach

Cited by 12 publications

References 28 publications

Identification of Markers of Saccharides in Polygonati Rhizoma During the Steaming Process by MALDI-TOF Mass Spectrometry Imaging

Identification of Markers of Saccharides in Polygonati Rhizoma During the Steaming Process by MALDI-TOF Mass Spectrometry Imaging

Traceability Research on Geographic Erigeron breviscapus Based on High-Resolution Mass Spectrometry and Chemometric Analysis

Traceability Research on Dendrobium devonianum Based on SWATHtoMRM

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