The global population faces a series of emerging conflicts related to marginalization and insecurity. The Mexican population also presents these signs as a result of the growing economic inequality that exacerbates social tensions whose evidence is the increase in violence and crime. Hence, the objective was to synthesize the problems presented by the Guadalajara Metropolitan Area (ZMG) between 2010 and 2019 regarding the degree of marginalization of its population from the point of view of geography. Methodology considered office work for the selection of publication that address the topics: indicators of marginalization and insecurity, complemented by field work such as the three exploratory tours in the area during 2017-2019. The results were: a) map of the ZMG and its conurbation in 2019; b) distribution of marginalization in the ZMG related to the type of road in 2019 and c) the degree of marginalization in relation to the location of the central municipalities and those outside the study area. Therefore, the conclusions were: 1) between 2010 and 2019 the standard of living of the ZMG population decreased since the marginalization index went from being mostly low to medium and 2) the public policies implemented between 2010-2019 failed to break with the delays and insecurity among the population residing in the ZMG, a trend that was consolidated at the national level.