[1] Enhancement of ocean alkalinity using calcium compounds, e.g., lime has been proposed to mitigate further increase of atmospheric CO 2 and ocean acidification due to anthropogenic CO 2 emissions. Using a global model, we show that such alkalinization has the potential to preserve pH and the saturation state of carbonate minerals at close to today's values. Effects of alkalinization persist after termination: Atmospheric CO 2 and pH do not return to unmitigated levels. Only scenarios in which large amounts of alkalinity (i.e., in a ratio of 2:1 with respect to emitted CO 2 ) are added over large ocean areas can boost oceanic CO 2 uptake sufficiently to avoid further ocean acidification on the global scale, thereby elevating some key biogeochemical parameters, e.g., pH significantly above preindustrial levels. Smaller-scale alkalinization could counteract ocean acidification on a subregional or even local scale, e.g., in upwelling systems. The decrease of atmospheric CO 2 would then be a small side effect. Citation: Ilyina, T., D. Wolf-Gladrow, G. Munhoven, and C. Heinze (2013), Assessing the potential of calcium-based artificial ocean alkalinization to mitigate rising atmospheric CO 2 and ocean acidification, Geophys. Res. Lett., 40,[5909][5910][5911][5912][5913][5914]