ABSTRACT. In [7,4], the first author and his collaborators constructed the irreducible symplectic 4-manifolds that are homeomorphic but not diffeomorphic to (2n − 1)CP 2 #(2n − 1)CP 2 for each integer n ≥ 25, and the families of simply connected irreducible nonspin symplectic 4-manifolds with positive signature that are interesting with respect to the symplectic geography problem. In this paper, we improve the main results in [7,4]. In particular, we construct (i) an infinitely many irreducible symplectic and non-symplectic 4-manifolds that are homeomorphic but not diffeomorphic to (2n − 1)CP 2 #(2n − 1)CP 2 for each integer n ≥ 12, and (ii) the families of simply connected irreducible nonspin symplectic 4-manifolds that have the smallest Euler characteristics among the all known simply connected 4-manifolds with positive signature and with more than one smooth structure. Our construction uses the complex surfaces of Hirzebruch and Bauer-Catanese on BogomolovMiyaoka-Yau line with c 2 1 = 9χ h = 45, along with the exotic symplectic 4-manifolds constructed in [2,5,3,6,10].