Detailed mapping and biostratigraphic data provide new evidence of a major break below the base of the Caradoc succession along the northern margin of the Harlech Dome in south central Snowdonia. Within this outcrop the sequence is locally complicated by subsequent tectonic and volcanic events, but undisturbed sections indicate a break of at least 10 Ma between upper Arenig and middle, or upper, Llandeilo strata. The break is greatest between two N-S trending fracture systems, the Cwm Pennant Fault Zone in the west and Trawsfynydd Fault Zone in the east, which both have a persistent history of reactivation. Between these two fractures neither Llanvirn nor lower Llandeilo strata occur. This contrasts with the thick, and perhaps complete, sequence preserved in the Cadair Idris district on the southern margin of the dome and suggests that, during Llanvirn times, the Harlech Dome formed a major uplifted and tilted block, with a tectonically active northern margin. Subsequently, uplift and tectonism either ceased before, or was overwhelmed by, the ensuing sea-level rise associated with the gracilis (early Caradoc) transgression. The preservation of ooidal ironstones around the dome suggests that it may have became a large shoal or platformal area at this time. Renewed uplift and erosion along the northern margin of the Harlech Dome during the early Caradoc (gracilis to multidens) led to large-scale disruption of the stratigraphic succession by mass gravity flow and slumping, overprinting and locally accentuating the effects of the earlier hiatus.