Grotta Romanelli can be counted among the most interesting sites for the late Upper Palaeolithic of the Mediterranean area, since returned a consistent record of lithic artefacts, faunal remains, mobiliary and parietal art, and human fossils which represent the least-known materials from the context. The resumption of the investigations in 2015, after 40 years of inactivity in the cave, provided relevant results. During the 2019 campaign, a distal phalanx of the hand was recovered in the so-called terre brune levels, providing for the first time a clear stratigraphic and chronological reference for the human fossils record of Grotta Romanelli. In addition to morphological description and age estimation, the new finding is here analyzed using 3D Micro-CT scans. The new human fossil confirms the exceptional richness of the paleoanthropological record of Grotta Romanelli, opening new avenues of investigation and posing crucial questions on the use of the cave and cultural practices at the Late Pleistocene-Holocene boundary.