Relevance. Modeling is the primary tool for understanding the surrounding world, processes, and phenomena. The models currently used by humanity are essentially fragmentary (discrete) with certain variations of correlative generalizations. Therefore, humanity is constantly seeking mathematical formulations that can encompass the full picture of the Universe.
Purpose. The aim of the research is to analyze the evolution of the theoretical and modeling foundation of the physical picture of the world with the identification of promising research vectors that have the potential to form broad generalized models of the Universe, in other words, the theory of Everything.
Methodology. To achieve this goal, methods of systematization and generalization, meta-analysis, and meta-synthesis were employed. Since this study is a review and is intended to systematize and deepen knowledge, its structure is unconventional.
Results. The current model of the scientific landscape is described, based on which the dynamic vectors of development of the theoretical foundation of the Universe theory were determined. This allowed us to conclude the current state of the system of physical modeling as the main tool for the civilizational development of mankind. The research suggests that at the current stage of development of ideas about the physical picture of the world, M-theory is a potential model of the theory of Everything.
Conclusions. The practical significance of the research results indicates a potential mathematical and theoretical concept (among existing theories and models) that is relevant and adequate to modern ideas about cosmogony, phenomena, and the structure of the Universe. This can attract more attention to a certain direction of scientific research, not only among the professional community but also among the general public