Analyzing the geochemical characteristics of hydrocarbons in Nepal is important to promote the exploration and development of hydrocarbons in Nepal. In this thesis, significant hydrocarbon geochemical anomalies in the Dailekh area of Nepal were revealed by comprehensive analysis of 12 indicators, including soil acid-dissolved hydrocarbons, post-generated carbonates (ΔC), conductivity (Ks), and adsorbed phase mercury (Hg). The analysis shows that the correlation between the indicators is good, and two anomalous zones are identified, located in the northwest and west-central part of the survey area, respectively, and the indicator anomalies in these zones show ring-in-ring top halo characteristics, especially Hg shows weak ring-strong top halo characteristics. These anomalies reflect the real geochemical activity information of the reservoir and verify the validity of this set of geochemical indicator combinations. The study further shows that these anomalies are mainly formed by the escape of underground oil and gas to the surface, and the favorable areas of anomalies No. I and No. II are presumed to be oil-type oil and gas reservoirs by the clustering analysis and hydrocarbon ratio method, indicating that this area has a good prospect for oil and gas exploration.