After the Industrial Revolution, 4.0 has shown the latest developments in all aspects of human life. Along with the presence of the Internet of Things and Artificial Intelligence, the quality of standard and religious human civilization has eroded. Verbal communication, civilized human communities, and spiritual life turn to virtual space, virtual communication, and applications. This paper aims to explain the role of theologians in providing the basis for the humanization of biblical civilization in the era of society 5.0. The research method with a qualitative approach and data collection with a literature study. The construction is that theologians play a part in fundamental biblical teaching and practice on humanizing civilization and building full human development locally and globally. The conclusion is that the role and steps of the theologian have a significant influence on the fundamental teaching of biblical human civilization amid a new civilization in the era of society 5.0 by maximizing the mix of methods in service and preaching.