German Register for Detection of Late Sequelae after Radiotherapy for Children and Adolescents (RiSK): Present Status and First Results

Second Malignant Neoplasms After Childhood Cancer in Germany – Results from the Long-term Follow-up of the German Childhood Cancer Registry

“…The progress in therapies, currently ¾ of all cases survive, is steadily increasing the number of survivors. The most serious late sequelae are second malignant neoplasms (SMN) [2,5,12]. Here we describe the current frequency of SMN at the GCCR.…”

Comparison of different adjuvant radiotherapy approaches in childhood bladder/prostate rhabdomyosarcoma treated with conservative surgery

“…In recent years, there has been increased interest to determine late effects due to the rising number of pediatric cancer survivors [2,3,9,20,33,47]. The theoretical disadvantage of BT relies in the inhomogeneous dose distribution with high dose peaks close to the catheters [18].…”

Radiation Toxicity Following Busulfan/Melphalan High-dose Chemotherapy in the EURO-EWING-99-trial: Review of GPOH Data

“…Radiation parameters including doses at organs at risk (bowel, spinal cord, lung) were obtained from the prospective database of the German "Registry for the evaluation of side effects after radiotherapy in childhood and adolescence" (RiSK). As this registry started in 2004 in a multricentric setting and only patients younger than 18 years have been included [2], additional data had to be obtained retrospectively from the treating radiotherapists using documentation forms compatible to the RiSK information. The toxicity was evaluated using EORTC/RTOG criteria.…”