2015
DOI: 10.1016/j.foodres.2015.04.041
|View full text |Cite
|
Sign up to set email alerts
|

Germination of Phaseolus vulgaris and alcalase hydrolysis of its proteins produced bioactive peptides capable of improving markers related to type-2 diabetes in vitro

Abstract: The aim of this study was to evaluate the effect of germination and alcalase hydrolysis of common bean proteins on the generation of bioactive peptides with potential to reduce parameters related to the risk of developing type-2 diabetes (T2D) in vitro. Germination (25°C up to 72 h) and alcalase hydrolysis (up to 4 h) produced peptides with high antioxidant capacity (1085 μmol TE/g soluble protein, SP). After 24 h of germination, there was an increase of 44% in α-amylase inhibitory capacity of the peptides rel… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

3
43
0
2

Year Published

2016
2016
2023
2023

Publication Types

Select...
6
2
1

Relationship

2
7

Authors

Journals

citations
Cited by 67 publications
(48 citation statements)
references
References 43 publications
3
43
0
2
Order By: Relevance
“…Based on our previous results on the biological potential of peptides from improved common bean cultivars, we selected four cultivars to further the investigation, using as important criteria their protein and peptide profiles. Black Otomi, BRS‐Horizonte, BRS‐Pontal and Perola presented good balance between agronomical‐related defense proteins and total proteins.…”
Section: Resultsmentioning
confidence: 99%
“…Based on our previous results on the biological potential of peptides from improved common bean cultivars, we selected four cultivars to further the investigation, using as important criteria their protein and peptide profiles. Black Otomi, BRS‐Horizonte, BRS‐Pontal and Perola presented good balance between agronomical‐related defense proteins and total proteins.…”
Section: Resultsmentioning
confidence: 99%
“…Germinated seeds have a high digestibility. Their components have been described with biological activities such as antioxidant, antitumoral, antibacterial and antihypertensive activities [22,23,24]. Germinated seeds can be used to obtain protein concentrates.…”
Section: Introductionmentioning
confidence: 99%
“…The soluble protein content was determined by following the instructions of the DC protein assay from Bio‐Rad that measured the reaction of protein with an alkaline copper tartrate solution and Folin reagent (de Souza Rocha et al, ). The results were expressed as grams of soluble protein per 100 g of dry flour.…”
Section: Methodsmentioning
confidence: 99%