Germline cytoskeletal and extra-cellular matrix-related single nucleotide variations associated with distinct cancer survival rates

Mucin expression, epigenetic regulation and patient survival: A toolkit of prognostic biomarkers in epithelial cancers

“…Additionally to gene expression, TCGA database was also analyzed regarding somatic gene mutation and relationship with OS. MUC4 and MUC17 germline mutations were associated with both better and worse survival rates depending on the organs [27]. MUC4, MUC5B and MUC16 mutations are associated with better patient survival in kidney cancer, eso-gastric and gastric cancer, respectively [28][29][30].…”