Gestational Age, Health, and Educational Outcomes in Adolescents

Berry, Mary J.; Foster, Tim; Rowe, Kate; Robertson, Oliver; Robson, Bridget; Pierse, Nevil

doi:10.1542/peds.2018-1016

Cited by 29 publications

(19 citation statements)

References 45 publications

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“…Active labor occurred most commonly after 6 cm of dilation, and cervical dilation progressed more slowly than previously thought, especially between 4 and 6 cm. These results represent a departure from the Friedman curve and now inform our clinical knowledge of median labor progression in modern obstetric practice [6] . Additionally, inherent differences in the progress of labor have been attributed to specific patient characteristics or clinical conditions.…”

Section: Introductionsupporting

confidence: 53%

“…Additionally, inherent differences in the progress of labor have been attributed to specific patient characteristics or clinical conditions. Maternal obesity, gestational age beyond 37 weeks and even fetal sex have been shown to influence labor progression [6] . In our study, we examined a contemporary labor database to identify labor curves and predictors of vaginal delivery in pregnant women undergoing medically indicated preterm IOL.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of preterm induction of labour

Shonali¹,

Shinge²

2021

Int. J. Clin. Obstet. Gynaecol.

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Introduction: Preterm labor is defined as regular uterine contractions occurring at least once every 10 minutes and resulting in cervical dilatation or effacement before 37 weeks' gestation. A preterm infant is any infant delivered before 37 weeks' gestation. Material and Methods: This is a prospective study conducted at Department of Obstetrics and Gynaecology, Subbaiah Institute of Medical Sciences, over a period of 1 year. All patients admitted in antenatal ward and labour room requiring preterm induction were included in this study. Pregnancies with major fetal anomalies or no intrapartum fetal monitoring were excluded. All patients were monitored in labour room with auscultation and non-stress test (NST). Mifepristone was given orally and Prostaglandin E2 (PGE2) gel was inserted in posterior fornix. Results: There was a total of 70 deliveries during this period. The preterm induction majorly includes 20-34 years as this is the commonest reproductive age group seen in our hospital. Multigravida requires induction more as compared to primigravida. More number of patients were induced between 32-36 weeks, reason being Preterm premature rupture of the membranes (PPROM), severe preeclampsia, intrauterine device (IUD) and severe Fetal growth restriction (FGR). 33% of the cases being induced due to PPROM, Fetal demise being the second cause of induction in our analysis. It is also interesting to note that HCC also contributes to be one of the causes of induction. 62.8% were induced via PGE2 gel. Out of 70 patients 87.1% of them delivered vaginally, 9 underwent lower segment Caesarean section (LSCS) i/v/o fetal distress and another one i/v/o Prolonged PROM. Conclusion:Our findings suggest that vaginal delivery is likely following preterm induction of labor (IOL) irrespective of gestational age. Parity and cervical favorability are the first and second strongest predictors of a successful vaginal delivery, respectively. Labor curves accelerate with each category of GA, ultimately approximating those observed following term IOL.

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Section: Introductionsupporting

confidence: 53%

Section: Introductionmentioning

confidence: 99%

Analysis of preterm induction of labour

Shonali¹,

Shinge²

2021

Int. J. Clin. Obstet. Gynaecol.

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“…Several studies have demonstrated a higher frequency of short and long term morbidity in early-term infants [ 3 , 4 , 5 ]. Neurodevelopmental outcomes of those infants are now being closely studied and initial reports focusing on cognition, school performance and behavioral problems demonstrate delays and deviations of the early-term infants as compared to the full-term infants [ 7 , 8 , 9 , 11 , 13 , 14 , 15 , 17 ]. Epilepsy and sensorineural defects have also been shown to be related to early-term deliveries [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

“…In addition to perinatal outcomes, infants born in the early-term period are considered to be at risk for adverse long-term outcomes in several aspects, especially in neurodevelopment [ 3 , 5 ]. It has been reported that compared with children born full-term, early-term birth has a negative impact on cognitive [ 6 , 7 ] and motor development [ 8 , 9 ], behavior and emotional status [ 8 , 10 , 11 ], communication skills and social outcomes [ 8 , 12 ], school performance and academic achievements [ 8 , 13 , 14 , 15 ]. However, there are large variations among published studies, including methodological diversity and heterogeneity of data [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Alberta Infant Motor Scale (AIMS) Performance of Early-Term Greek Infants: The Impact of Shorter Gestation on Gross Motor Development among “Term-Born” Infants

et al. 2022

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Early-term birth (37+0 to 38+6 gestational weeks) may have a negative impact on infants’ neurodevelopment compared to delivery at 39 weeks or beyond. The purpose of this study was to evaluate the gross motor development of early-term infants using the Alberta Infant Motor Scale (AIMS). A total of 1087 healthy infants (559 early-term and 528 full-term infants born at 39+0 to 41+6 weeks of gestation) were studied. Mean AIMS scores were compared between the two groups at monthly intervals. The impact of gestational age on total AIMS scores was assessed by linear regression, after adjustment for chronological age, sex and SGA. Mean total AIMS scores, albeit within normal range, were significantly lower in early-term than full-term infants at the 2nd, 6th, 7th, 8th and 12th month of age; differences between groups were within three points. In multivariate regression analysis, a longer gestation by one week had a positive impact on total AIMS score during the first year of life (β = 0.90; 95% CI 0.45, 1.35). In conclusion, early-term infants exhibit worse gross motor performance during the first year of life in comparison with their full-term peers; however, the differences between the two groups are small.

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“…Late preterm infants (34 +0 -36 +6 weeks' gestation) comprise the majority of preterm births, 1 2 and are physiologically and metabolically immature, 3 with a higher risk of morbidity and mortality in the neonatal period than term infants. 4 Late preterm infants are more likely to be diagnosed with cerebral palsy, 5 6 developmental delay [7][8][9] and cognitive impairment [9][10][11][12][13] compared with term infants. Late preterm infants also experience frequent episodes of intermittent hypoxaemia (IH) 14 ; transient repetitive decreases in oxygen saturation not associated with apnoea but potentially causing similar organ hypoxia.…”

Section: Introductionmentioning

confidence: 99%

Caffeine to prevent intermittent hypoxaemia in late preterm infants: randomised controlled dosage trial

Oliphant

McKinlay

McNamara

et al. 2022

Arch Dis Child Fetal Neonatal Ed

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ObjectiveTo establish the most effective and best tolerated dose of caffeine citrate for the prevention of intermittent hypoxaemia (IH) in late preterm infants.DesignPhase IIB, double-blind, five-arm, parallel, randomised controlled trial.SettingNeonatal units and postnatal wards of two tertiary maternity hospitals in New Zealand.ParticipantsLate preterm infants born at 34+0–36+6 weeks’ gestation, recruited within 72 hours of birth.InterventionInfants were randomly assigned to receive a loading dose (10, 20, 30 or 40 mg/kg) followed by 5, 10, 15 or 20 mg/kg/day equivolume enteral caffeine citrate or placebo daily until term corrected age.Primary outcomeIH (events/hour with oxygen saturation concentration ≥10% below baseline for ≤2 min), 2 weeks postrandomisation.Results132 infants with mean (SD) birth weight 2561 (481) g and gestational age 35.7 (0.8) weeks were randomised (24–28 per group). Caffeine reduced the rate of IH at 2 weeks postrandomisation (geometric mean (GM): 4.6, 4.6, 2.0, 3.8 and 1.7 events/hour for placebo, 5, 10, 15 and 20 mg/kg/day, respectively), with differences statistically significant for 10 mg/kg/day (GM ratio (95% CI] 0.39 (0.20 to 0.76]; p=0.006) and 20 mg/kg/day (GM ratio (95% CI] 0.33 (0.17 to 0.68]; p=0.003) compared with placebo. The 20 mg/kg/day dose increased mean (SD) pulse oximetry oxygen saturation (SpO2) (97.2 (1.0) vs placebo 96.0 (0.8); p<0.001), and reduced median (IQR) percentage of time SpO2 <90% (0.5 (0.2–0.8) vs 1.1 (0.6–2.4); p<0.001) at 2 weeks, without significant adverse effects on growth velocity or sleeping.ConclusionCaffeine reduces IH in late preterm infants at 2 weeks of age, with 20 mg/kg/day being the most effective dose.Trial registration numberACTRN12618001745235.

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Gestational Age, Health, and Educational Outcomes in Adolescents

Cited by 29 publications

References 45 publications

Analysis of preterm induction of labour

Analysis of preterm induction of labour

Alberta Infant Motor Scale (AIMS) Performance of Early-Term Greek Infants: The Impact of Shorter Gestation on Gross Motor Development among “Term-Born” Infants

Caffeine to prevent intermittent hypoxaemia in late preterm infants: randomised controlled dosage trial

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