Objective:The aim of this study was to research the rates of diabetes mellitus (DM) and the risk factors that may play a role in the prediction of this condition by evaluating patients with the diagnosis of gestational diabetes mellitus (GDM) at the 6 th -12 th postpartum months.
Material and Method:Among 109 cases who had been invited to the hospital for oral glucose tolerance test (OGTT) at the 6 th -12 th postpartum months, 84 cases (77%) were enrolled in the study. To the 78 patients that were found to be appropriate according to the study criteria, 75 gr OGTT was administered. Patients who had new pregnancies during the period of postpartum screening, and those with previously diagnosed DM were excluded from the study.
Results:While the results of 23 cases (29.5%) included in the study were normal, 27 cases (34.6%) were diagnosed with DM and 28 cases (35.9%) were diagnosed as having an impaired glucose tolerance and /or impaired fasting glucose (IGT/IFG). Among patients diagnosed with DM, the history of DM in the first degree relatives (n=21, 77.8%, p=0.018), body mass index before pregnancy (mean=30.1±4.4, p=0.009) and insulin requirement for the treatment of GDM (n=25, 92.6%, p<0.05) were determined at higher rates. In the logistic regression analysis, multiparity (OR=2) and insulin requirement during pregnancy (OR: 7.27) were found to be the predictive factors in the development of postpartum DM.
Discussion:In this study, the determination of high rates of DM development in the postpartum period after GDM demonstrates the necessity of augmentation in efforts to increase the screening rates after delivery and to increase the patients' acknowledgement of this topic. (J Turkish-German Gynecol Assoc 2010; 11: 89-94) Key words: Gestational diabetes mellitus, postpartum, OGTT Received: 20 February, 2010 Accepted: 11 April, 2010 Amaç: Bu çalışmada gestasyonel diyabetes mellitus (GDM) tanısı alan hastaların postpartum 6-12.aylar arasında değerlendirilmesi sonucunda diyabetes mellitus (DM) saptanma oranları ve bu durumun öngörülmesine katkısı olabilecek risk faktörlerini araştırmak amaç-lanmıştır.
Gereç ve Yöntemler:Postpartum 6-12. aylar arasında oral glikoz tolerans testi (OGTT) için hastaneye davet edilen 109 hastadan 84 (%77) olgu çalışmaya başvurdu, çalışma kriterlerine uygun 78 hastaya 75 gr OGTT uygulandı. Postpartum tarama zamanında tekrar gebelik tespit edilen veya daha önce DM tanısı alan hastalar çalışma dışı bırakıldı.
Bulgular:Çalışma kapsamındaki hastalardan 23 (%29.5) olgunun sonuçları normalken; 27 olguya (%34.6) DM, 28 (%35.9) olguya bozulmuş glikoz toleransı ve/veya bozulmuş açlık glikozu tanısı konuldu. DM tanısı alan hasta grubunda 1.derece akrabalarda DM öyküsü (n=21, %77.8, p=0.018), gebelik öncesi vücut kitle indeksi (ortalama=30.1±4.4, p=0.009) ve GDM tedavisi için insülin gereksinimi (n=25, %92.6, p<0.05) daha fazla oranda tespit edildi. Yapılan lojistik regresyon analizi sonucunda multiparite (OR=2) ve gebelikte insülin tedavisi gereksiniminin (OR: 7.27) postpartum DM gelişimi iç...