Gestational weight gain and glycemic control in GDM patients with positive genital culture

The impact of COVID-19 in pregnancy: Part I. Clinical presentations and untoward outcomes of pregnant women with COVID-19

“…28–34 Moreover, overweight (obesity) and advanced age (for example, ≥35 years of age) are also frequently noted in modern obstetrics, resulting in worse outcomes of pregnancy. 35–39 All of them have been known as well correlation with adverse pregnancy outcomes, regardless of concomitance with SARS-CoV-2 infection or not. 6,9,11,12,14,26–66…”

“…35–39 All of them have been known as well correlation with adverse pregnancy outcomes, regardless of concomitance with SARS-CoV-2 infection or not. 6,9,11,12,14,26–66…”

To do one and to get more: Part I. Diabetes and bone

“…Diabetes mellitus (DM), including type 1 DM (T1DM) and type 2 DM (T2DM), is a common but complex disease, associated with lots of comorbidities and a leading cause of mortality. [1][2][3][4][5][6][7][8] Risk factors associated with developing DM, especially T2DM accounting for >90% of all cases of DM worldwide, include elderly population, [9][10][11] family history (multiple genes), [11][12][13][14][15][16][17][18] overweight, 3,4,[17][18][19][20][21] obesity, 3,4,[17][18][19][20][21] pregnancy, such as the development of gestational DM, [21][22][23][24] dietary (calories intake, fibers, essential micronutrition, and mineral elements), [25][26][27][28][29] lifestyle factors (exercise, rest, and others), 3,4,[30][31][32]<...…”

“…9,10 Lifestyle modification, such as caloric restriction, body weight reduction (in part, through reducing extrinsic insulin resistance), regular and appropriate exercise, and others, is recommended as firstline therapy to manage prediabetes and DM. [21][22][23][24]27,28,[30][31][32]36 The major strength of lifestyle modification is based on its safety and potential effectiveness, which are considered as overt benefits to harms. [37][38][39] However, DM patients have a tendency to lower total adherence to healthy eating patterns or poorer consumption of major food groups (grains, fruits, vegetables, proteins, seeds, nuts, and dairy) 17,18,30,31 ; therefore, many DM patients still need further pharmacologic agent therapy (antidiabetic agents [ADAs], glucose-lowering drugs) to overcome the underlying pathophysiological mechanisms of DM, such as inadequate and inappropriate secretion of insulin, defect and deficiency of insulin receptor, and malfunction about interaction of insulin and insulin receptor.…”

“…Diabetes mellitus (DM), including type 1 DM (T1DM) and type 2 DM (T2DM), is a common but complex disease, associated with lots of comorbidities and a leading cause of mortality. 1–8 Risk factors associated with developing DM, especially T2DM accounting for >90% of all cases of DM worldwide, include elderly population, 9–11 family history (multiple genes), 11–18 overweight, 3,4,17–21 obesity, 3,4,17–21 pregnancy, such as the development of gestational DM, 21–24 dietary (calories intake, fibers, essential micronutrition, and mineral elements), 25–29 lifestyle factors (exercise, rest, and others), 3,4,30–32 environmental factors, interactions with other microorganisms (microbiotas), and many others. 33–35 The key pathophysiologic mechanism of DM is based on the inability of faulty pancreatic β-cells to secret a normal amount of insulin to maintain normal body consumption, and/or peripheral tissue has a decreased susceptibility to insulin, resulting in hyperglycemia and insulin resistance.…”