In this study, the fifth-generation Pennsylvania State University-National Center for Atmospheric Research (PSU-NCAR) Mesoscale Model (MM5) is used to simulate Typhoon Rananim (2004) at high resolution (2-km grid size). The simulation agrees well with a variety of observations, especially for intensification, maintenance, landfall, and inner-core structures, including the echo-free eye, the asymmetry in eyewall convection, and the slope of the eyewall during landfall. The asymmetric feature of surface winds is also captured reasonably well by the model, as well as changes in surface winds and pressure near the storm center.The shear-induced vortex tilt and storm-relative asymmetric winds are examined to investigate how vertical shear affects the asymmetric convection in the inner-core region. The inner-core vertical shear is found to be nonunidirectional, and to induce a nonunidirectional vortex tilt. The distribution of asymmetric convection is, however, inconsistent with the typical downshear-left pattern for a deep-layer shear. Qualitative agreement is found between the divergence pattern and the storm-relative flow, with convergence (divergence) generally associated with asymmetric inflow (outflow) in the eyewall. The collocation of the inflow-induced lower-level convergence in the boundary layer and the lower troposphere and the midlevel divergence causes shallow updrafts in the western and southern parts of the eyewall, while the deep and strong upward motion in the southeastern portion of the eyewall is due to the collocation of the net convergence associated with the strong asymmetric flow in the midtroposphere and the inflow near 400 hPa and its associated divergence in the outflow layer above 400 hPa.