Ghrelin and melatonin as biomarkers in patients with giardiasis

Al-Hadraawy, Saleem Khteer; Al-ghurabi, Mohammed Emad; Al-musawi, Malak Maged; Alzeyadi, Mohammad

doi:10.1080/13102818.2016.1149038

Cited by 14 publications

(4 citation statements)

References 27 publications

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“…In this investigation, samples were compared using the T-test with Graph-Pad Prism version 10 software. A p-value of 0.05 or less is regarded as statistically significant (14,15,16).…”

Section: Discussionmentioning

confidence: 99%

Study the Role of Eosinophilic Cationic Protein, Copper and Iron in Women Infected with Trichomonas vaginalis Parasite

haider¹,

ALhadrawi²,

Al-Hadraawy³

et al. 2022

Journal of Pharmaceutical Negative Results

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Since Trichomonas vaginalis (T. vaginalis) only manifests as a trophozoite stage during sex, it is typically transmitted during sex as a trophozoite. The purpose of this study was to determine the concentrations of copper, iron, and Eosinophil cationic protein (ECP) in vaginitis patients. Between July and November 2021, 355 suspected patients who visited the AL-Zahra maternity and pediatrics laboratory in the AL-Najaf region (Iraq) and 30 healthy respondents of the same age participated in the study. According to the manufacturer's instructions, the ELISA technique was used to measure the levels of three biomarkers in serum (copper, iron, and ECP). On the other hand, the colorimetric approach was used to measure the copper concentration. The investigation showed that in the blood sample of T. vaginalis-infected patients, the amounts of copper and iron considerably decreased (P > 0.05). In contrast, the serum levels of ECP considerably increased (P > 0.05) when compared to the control group. As a result of the T. vaginalis infection, copper levels in the blood are dramatically impacted, according to the current study's findings. The current study results suggested that the T. vaginalis infection alters serum iron and ECP concentrations, significantly affecting copper levels in the blood.

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“…In this investigation, samples were compared using the T-test with Graph-Pad Prism version 10 software. A p-value of 0.05 or less is regarded as statistically significant (14,15,16).…”

Section: Discussionmentioning

confidence: 99%

Study the Role of Eosinophilic Cationic Protein, Copper and Iron in Women Infected with Trichomonas vaginalis Parasite

haider¹,

ALhadrawi²,

Al-Hadraawy³

et al. 2022

Journal of Pharmaceutical Negative Results

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show abstract

“…18 The present study disagrees with the finding of Ma'ani N et al 17 in Iraq that reported a normal value of HDL in patients with giardiasis, while being consistent with various studies which found higher concentrations of serum HDL in patients infected with G. Lamblia parasite in comparison with the healthy group. 9,18,19,20,23,24 HDL was considered a major carrier in circulation and plays a role in metabolism and transport, and in preventing cholesterol accumulation in the cells of the artery wall. 25…”

Section: Discussionmentioning

confidence: 99%

Mucin2 and Lipid Profile Estimation in Giardia Lamblia Infected Patients: A Case-control Study

Hassan

2022

JCD

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Introduction: Globally, Giardia duodenalis (G. lamblia) is a protozoan parasite that has the ability to cause sporadic or epidemic infectious diarrhoea. Giardia infection is a crucial cause of waterborne and foodborne disease, outbreaks in the daycare centre, and international travel-related infection. This study aimed to evaluate the effects of Giardia lamblia infection on serum MUC2 and lipid profile. Patients and Methods: From March to April 2021, a case-control study was conducted on 48 patients with giardiasis who attended AL-Hakeem Hospital in Najaf Province in Iraq and 24 healthy adults as a control group. Stool examinations were done using standard techniques for the identification of the parasitic infection. Results: The results showed a significantly higher concentration (130.57 ± 4.04 ng/ml, and 130.11 ± 3.6 ng/ml) (p < 0.05 of MUC2 in G. lamblia infected patients (males and females) in comparison to the individuals of the control group. In addition, significantly higher concentrations (p < 0.05) of cholesterol, VLDL, TG, and LDL were found in comparison to the control individuals, whereas the concentration of HDL was significantly lower (p < 0.05 in patients infected with G. lamblia as compared to the control group. Conclusion: The current study revealed that MUC2 and lipid profile are valuable biomarkers that help in the diagnosis of G. lamblia parasite infection.

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“…[58], who found in their study in Najaf province where they found I, II, and III with the frequency of 60 %, 25 %, and 15% respectively. These results disagree with findings in other locations of Iraq such asMohammed et al [59] in Baghdad, and Aziz[60] in Wasit who found the dominant genotype is II, and Al-Khanak, and Salman [63] in Wasit who found that genotype III is the dominance.In Egypt, Abdel-Hameed and Hassanein[61] found that genotype II is the most frequent at 87 % and genotype I at 13 % but they do not find genotype III.…”

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confidence: 85%

Using Antibody rapid test, RT-qPCR, and RFLP/PCR for detecting Toxoplasma gondii in the placenta of abortion women and determining the genotype in Maysan province, Iraq .

Safaa Salman Allamy,

Hussain A. Mhouse Alsaady

2023

JWSM

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Toxoplasma gondii is one of the obligatory intracellular protozoan parasites that are important and widespread in all developing or developed countries. It infects all nucleated cells of warm-blooded animals. This study used the lateral flow immunoassay (LFIA), real-time quantitative polymerases chain reactions (RT-qPCR) for detecting the T. gondii in blood and placental tissues, in addition to the restriction fragment length polymorphism (RFLP) technique to determine the genotypes/strains of T. gondii in Maysan province. The study included 40 participating women, distributed as 22 aborted women and 18 without abortion. The LFIA detected that the seropositive rate of anti-T. gondii IgG is 38.9 % and with the using RT-qPCR technique, the infection rate is 10 % and 0.0 % among placenta and sera. it also, showed that 85.7 % of all T. gondii infections are found in aborted women, compared with 14.3 % without abortion. In contrast, it showed that 63.6 % of T. gondii seronegative are women without abortion, compared to 36.4 % among aborted women. The PCR-RFLP technique has identified the main three genotypes “I, II, and III” of T. gondii in Ammara city, and showed that genotype "I" is the most frequent at 50% (6/12) than genotypes II, 4/12 (33.33 %), and III, 2/12 (16.67 %).

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Ghrelin and melatonin as biomarkers in patients with giardiasis

Cited by 14 publications

References 27 publications

Study the Role of Eosinophilic Cationic Protein, Copper and Iron in Women Infected with Trichomonas vaginalis Parasite

Study the Role of Eosinophilic Cationic Protein, Copper and Iron in Women Infected with Trichomonas vaginalis Parasite

Mucin2 and Lipid Profile Estimation in Giardia Lamblia Infected Patients: A Case-control Study

Using Antibody rapid test, RT-qPCR, and RFLP/PCR for detecting Toxoplasma gondii in the placenta of abortion women and determining the genotype in Maysan province, Iraq .

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