Ghrelin level and types of eating behavior when combined with irritable bowel syndrome, arterial hypertension and obesity

Abstract

Le niveau de la ghréline et les types d'habitude alimentaire lors de la combinaison du syndrome de l'intestin irritable, de l'hypertension artérielle et de l'obésité Contexte. La ghréline régule la motilité du tractus gastro-intestinal, la nature du comportement alimentaire, a un effet cardioprotecteur, augmente la vasodilatation et régule la tension artérielle. Objectif. Etudier le niveau de la ghréline basale et postprandiale chez les patients présentant une combinaison de l'hypertension, le syndrome du côlon irritable sur le fond de l'obésité et du comportement alimentaire. Méthodes. L'étude a porté sur 24 patients avec syndrome du côlon irritable, constipation, poids normal, 18 patients avec de l'hypertension de 2-ème degré sur le fond de l'obésité et 54 patients souffrant de troubles concomitants (syndrome du côlon irritable avec constipation sur le fond de l'hypertension et l'obésité I-III).

Crosstalk between Oxidative Stress and Inflammation in Obesity

“…According to the World Health Organization (WHO) definition of overweight and obesity, an overweight subject has a body mass index (BMI) of 25 to 29.9 kg/m 2 , whereas the BMI of an obese subject exceeds 30 kg/m 2 . Recent studies have underlined that, in obese subjects, the adipose tissue dysfunction derives also from the interplay between reactive oxygen species (ROS) signalling and inflammatory response pathways [1][2][3][4][5][6][7][8][9].Oxidative stress, defined as the imbalance between the production of ROS and the levels of antioxidants in the body, is a key element in the development of obesity and many obesity-related comorbidities. The main ROS involved in this process are the superoxide anion • O2 -, the hydrogen peroxide H2O2 and the hydroxyl radical • OH, whereas antioxidant enzymes, i.e.…”

“…According to the World Health Organization (WHO) definition of overweight and obesity, an overweight subject has a body mass index (BMI) of 25 to 29.9 kg/m 2 , whereas the BMI of an obese subject exceeds 30 kg/m 2 . Recent studies have underlined that, in obese subjects, the adipose tissue dysfunction derives also from the interplay between reactive oxygen species (ROS) signalling and inflammatory response pathways [1][2][3][4][5][6][7][8][9].…”