Ghrelin, neuropeptide Y (NPY) and cholecystokinin (CCK) in blunt snout bream (Megalobrama amblycephala): cDNA cloning, tissue distribution and mRNA expression changes responding to fasting and refeeding

Ji, Wei; Ping, Hongzheng; Wei, Kai-Jian; Zhang, Guirong; Shi, Ze-Chao; Yang, Ruibin; Zou, Guiwei; Wang, Weimin

doi:10.1016/j.ygcen.2015.08.009

Cited by 64 publications

(46 citation statements)

References 60 publications

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“…The cck mRNA levels decrease by fasting in different fish species (Murashita et al, 2006;Feng et al, 2012;Ji et al, 2015), conversely ghrelin increase mRNA levels by fasting (Amole & Unniappan, 2009;Zhou & Xue, 2009;Tian et al, 2015;Volkoff, 2015;Blanco et al, 2016). These gene expression modulations were not observed in our results.…”

Section: Discussioncontrasting

confidence: 72%

Comparison of gene expression patterns of key growth genes between different rate growths in zebrafish (Danio rerio) siblings

Opazo¹,

Valladares²,

Romero³

2017

lajar

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ABSTRACT. Variable individual growth rate is a phenomenon observed in fish cohorts that influences the aquaculture performance and fish cohort ecological viability. Our aim was to compare gene expression patterns of key growth genes in zebrafish larvae with different growth rate. The body length of sibling zebrafish larvae at 6 days post hatching (dph) was measured. The larvae were reared to 20 dph and measured again. Two bodylength groups were clearly observed: 4 mm (small larvae) and 5-6 mm (large larvae). Total RNA was isolated from both groups. Growth hormone (gh), growth hormone receptor (ghr), insulin-like growth factor 1 (igf-1), insulin-like growth factor receptor (igf-1r a/b), insulin-like growth factor binding protein 1 (igfbp-1), thyroglobulin (tg), cholecystokinin (cck), and ghrelin were evaluated by quantitative polymerase chain reaction (qPCR). Glucokinase (gck) and igfbp-1 were included as a gene expression marker of larvae nutritional status. Two genes showed significant differences between the body length groups, igfbp-1 (P = 0.01) and igf-1r (P = 0.02). The igfbp-1 suggests than growth rate variability was associated with the larvae nutritional status and this condition affect the gene expression pattern of igf-1r. Therefore these genes are interesting genes markers for growth rate variabilities studies.

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Section: Discussioncontrasting

confidence: 72%

Comparison of gene expression patterns of key growth genes between different rate growths in zebrafish (Danio rerio) siblings

Opazo¹,

Valladares²,

Romero³

2017

lajar

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“…The first direct evidence of the actions of CCK on feeding was provided by injections in goldfish (Himick and Peter, 1994), followed by cloning of goldfish CCK cDNA (Peyon et al, 1998) and the demonstration of periprandial variations in CCK mRNA expression levels (Peyon et al, 1999). Subsequently, a number of studies have characterized CCK in several fish, including other Cypriniformes (e.g., common carp Zhong et al, 2013; zebrafish Koven and Schulte, 2012; Tian et al, 2015; grass carp; blunt snout bream Ping et al, 2013; Ji et al, 2015), Characiformes (e.g., cavefish Wall and Volkoff, 2013, dourado Pereira et al, 2015; Volkoff et al, 2016, thin dogfish Oligosarcus hepsetus Vieira-Lopes et al, 2013, pirapitinga Volkoff, 2015a, red-bellied piranha Volkoff, 2014a, pacu Volkoff et al, 2017), Salmoniformes (e.g., Atlantic salmon Valen et al, 2011), Gadiformes (Atlantic cod Tillner et al, 2013), Perciformes [e.g., yellowtail (Furutani et al, 2013; Hosomi et al, 2014); Astatotilapia burtoni (Grone et al, 2012); cunner (Babichuk and Volkoff, 2013; Hayes and Volkoff, 2014); sea bass (Tillner et al, 2014); yellow croaker ( Larimichthys crocea ) (Cai et al, 2015); white sea bream, Diplodus sargus (Micale et al, 2012, 2014)], Pleuronectiformes (e.g., winter flounder (MacDonald and Volkoff, 2009a), Atlantic halibut Kamisaka et al, 2001, olive flounder Kurokawa et al, 2000) and Siluriformes (channel catfish Peterson et al, 2012). …”

Section: Hormones Involved In Food Intakementioning

confidence: 99%

The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge

2016

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Fish are the most diversified group of vertebrates and, although progress has been made in the past years, only relatively few fish species have been examined to date, with regards to the endocrine regulation of feeding in fish. In fish, as in mammals, feeding behavior is ultimately regulated by central effectors within feeding centers of the brain, which receive and process information from endocrine signals from both brain and peripheral tissues. Although basic endocrine mechanisms regulating feeding appear to be conserved among vertebrates, major physiological differences between fish and mammals and the diversity of fish, in particular in regard to feeding habits, digestive tract anatomy and physiology, suggest the existence of fish- and species-specific regulating mechanisms. This review provides an overview of hormones known to regulate food intake in fish, emphasizing on major hormones and the main fish groups studied to date.

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“…Partial and complete mRNA sequences of CCK are available for a number of fish species, and CCK-like-ir is present in gut and nervous system of several teleost species (Jönsson et al, 1987; Micale et al, 2012, 2014; Ji et al, 2015). CCK-like peptides are potent anorexigenic signals in fish (Himick and Peter, 1994; Volkoff et al, 2005; Rubio et al, 2008; MacDonald and Volkoff, 2009; White et al, 2016).…”

Section: Hypothalamic Integration Of Endocrine Informationmentioning

confidence: 99%

“…CCK-8 may be involved in the seasonal changes of food intake experienced by salmonids (White et al, 2016), and starvation challenge experiments support the anorexigenic action of CCK-8 in fish. The expression levels of CCK mRNA decreased in brain and intestine after starvation in different fish species (Murashita et al, 2006; Feng et al, 2012; Ji et al, 2015), while CCK is released after feeding in intestine (Aldman and Holmgren, 1995). The mechanisms underlying the anorexigenic effect of CCK-like peptides are unknown, but the lack of effect after peripheral administration in channel catfish (Schroeter et al, 2015) suggests that anorexigenic action occur at the central level.…”

Section: Hypothalamic Integration Of Endocrine Informationmentioning

confidence: 99%

Hypothalamic Integration of Metabolic, Endocrine, and Circadian Signals in Fish: Involvement in the Control of Food Intake

2017

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The regulation of food intake in fish is a complex process carried out through several different mechanisms in the central nervous system (CNS) with hypothalamus being the main regulatory center. As in mammals, a complex hypothalamic circuit including two populations of neurons: one co-expressing neuropeptide Y (NPY) and Agouti-related peptide (AgRP) and the second one population co-expressing pro-opiomelanocortin (POMC) and cocaine- and amphetamine-regulated transcript (CART) is involved in the integration of information relating to food intake control. The production and release of these peptides control food intake, and the production results from the integration of information of different nature such as levels of nutrients and hormones as well as circadian signals. The present review summarizes the knowledge and recent findings about the presence and functioning of these mechanisms in fish and their differences vs. the known mammalian model.

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Ghrelin, neuropeptide Y (NPY) and cholecystokinin (CCK) in blunt snout bream (Megalobrama amblycephala): cDNA cloning, tissue distribution and mRNA expression changes responding to fasting and refeeding

Cited by 64 publications

References 60 publications

Comparison of gene expression patterns of key growth genes between different rate growths in zebrafish (Danio rerio) siblings

Comparison of gene expression patterns of key growth genes between different rate growths in zebrafish (Danio rerio) siblings

The Neuroendocrine Regulation of Food Intake in Fish: A Review of Current Knowledge

Hypothalamic Integration of Metabolic, Endocrine, and Circadian Signals in Fish: Involvement in the Control of Food Intake

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