Giant Cell Arteritis Among Hispanic Americans

Lam, Byron L.; Wirthlin, R.; Gonzalez, A.; Dubovy, Sander R.; Feuer, William J.

doi:10.1016/j.ajo.2006.07.048

Cited by 31 publications

(19 citation statements)

References 6 publications

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“…It is interesting to note that none of the 40 Hispanic patients had a positive biopsy. One recent study by Lam et al of patients who underwent temporal artery biopsies in Miami refutes this, showing that the prevalence of GCA was similar between Hispanic and non-Hispanics [35]. This may be explained by the fact that race was self-identified by the patients via telephone interview, rather than by retrospective review of medical charts.…”

Section: Agementioning

confidence: 92%

“…The mechanisms of increased female propensity to autoimmunity remain unclear, although epigenetic influences, including X monosomy and the role of estrogens, have been suggested [34][35][36]. The highest female to male ratio reported has been 7.7:1 in Shelby County, Tennessee [26]; however, given that the sample size of the study was quite low (26 patients in all), it may be difficult to interpret this number.…”

Section: Agementioning

confidence: 97%

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The Geo-epidemiology of Temporal (Giant Cell) Arteritis

Lee

Naguwa

Cheema

et al. 2008

Clinic Rev Allerg Immunol

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Giant cell arteritis (GCA) is the most common vasculopathy in patients over the age of 50. The majority of data on the geo-epidemiology of GCA is derived from Scandinavia, although there is very good documentation and epidemiological descriptions from studies throughout Europe and North America. There remains, however, a paucity of data on the incidence and prevalence of GCA in North American minority populations, as well as from Africa or Asia. The data that does exist suggests that the incidence of GCA is lower in Hispanic, Asian, and African American populations. It is interesting to note that as the population throughout the world continues to age, we anticipate an increased prevalence of disease based upon increases in annual incidence and improved survival. Considerable research is still needed to identify genetic, environmental, and gender-specific factors that influence not only the etiology, but also the natural history of disease.

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Section: Agementioning

confidence: 92%

Section: Agementioning

confidence: 97%

The Geo-epidemiology of Temporal (Giant Cell) Arteritis

Lee

Naguwa

Cheema

et al. 2008

Clinic Rev Allerg Immunol

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“…However, more recent data suggests that the prevalence and clinical course of GCA is similar in Hispanics to that of non-Hispanic patients (Lam et al, 2007).…”

Section: Epidemiologymentioning

confidence: 97%

Giant Cell Arteritis

Tehrani

Ostrowski

Hariman

et al. 2008

Seminars in Ophthalmology

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This review summarizes the diagnosis, clinical manifestations and management of giant cell arteritis. Giant cell arteritis is an immune-mediated vasculitis of medium to large sized arteries that affects individuals older than the age of 50. Patients typically present with signs of vascular insufficiency of the extracranial arteries of the head and systemic inflammation. Temporal artery biopsy remains the hallmark of diagnosis. Specific treatment regimens must be tailored to each individual, but steroids remain the backbone of therapy.

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“…1−3 It is rare in Asians and was also believed to be rare in Hispanics, but more recent data from the United States suggests that the prevalence and clinical course of GCA is similar in Hispanics to that of non-Hispanic patients. 4 The backbone of therapy for GCA remains corticosteroids, however, the dosage, route of administration and maintenance dose remains debatable. There is a significant incidence of persisting visual loss even after treatment is commenced 5 but the question of whether either oral or intravenous corticosteroids is superior in preventing vision loss or decreasing the progression of the vision loss if present has yet to be answered.…”

Section: Introductionmentioning

confidence: 99%

Giant Cell Arteritis: Oral Versus Intravenous Corticosteroids

Tehrani

Ostrowski

Hariman

et al. 2009

Neuro-Ophthalmology

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This review summarizes the current literature on the use of oral versus intravenous steroids for giant cell arteritis. Giant cell arteritis is an immune-mediated vasculitis of medium to large sized arteries that affects individuals older than the age of fifty. Patients typically present with signs of vascular insufficiency of the extracranial arteries of the head and systemic inflammation. Steroids remain the backbone of therapy, but the dose, maintenance and route of administration remain debatable.

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Giant Cell Arteritis Among Hispanic Americans

Abstract: Purpose-To compare the prevalence and clinical course of giant cell arteritis (GCA) among Hispanic and non-Hispanic patients.

Cited by 31 publications

References 6 publications

The Geo-epidemiology of Temporal (Giant Cell) Arteritis

The Geo-epidemiology of Temporal (Giant Cell) Arteritis

Giant Cell Arteritis

Giant Cell Arteritis: Oral Versus Intravenous Corticosteroids

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