Giant-Cell Arteritis — An Acute Hand Syndrome

Bugg, Everett I.; Coonrad, Ralph W.; Grim, Kenneth B.

doi:10.2106/00004623-196345060-00015

Cited by 19 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…He became asymptomatic with Dexamethasone 12 mg/day (Bethlenfalvay Nusynowitz, 1964). Bugg et al (1963)reported 3 cases (ages 64, 36 and 44) with painful hands. Biopsy of the radial, ulnar and median arteries in these patients showed 'giant cell arteritis'; no temporal artery biopsy was done; none of the patients had systemic symptoms; none were given steroids.…”

Section: Juvenile Temporal Arteritismentioning

confidence: 99%

Controversies regarding Giant cell (Temporal, Cranial) arteritis

Eshaghian

1979

Doc Ophthalmol

View full text Add to dashboard Cite

It is important to establish the diagnosis of temporal arteritis because the disease is treatable; treatment may prevent blindness and even death. Temporal arteritis usually occurs in people older than 51 years of age, although very rarely, histologically documented disease occurs in younger people. The onset may be occult, so that there are few findings. A multitude of signs and symptoms may occur such as fever, headaches, malaise, weight loss, anemia, stroke, cranial nerve palsies, polymyalgia rheumatica, aortitis and other large vessel involvement. The eye may suffer from ischemic optic neuropathy (anterior or posterior), central or cilio-retinal arterial occlusion, ophthalmic artery ischemia, or extraocular muscle palsies. An arterial biopsy showing giant cell arteritis establishes the diagnosis. However, a negative biopsy does not rule out the disease because of the occasional presence of skip areas. Arteriography has only rarely yielded a positive temporal artery biopsy when the initial biopsy done elsewhere was negative. As a diagnostic parameter, the erythrocyte sedimentation rate is nonspecific, being elevated in diseases other than temporal arteritis and sometimes being falsely lowered by technical factors. Furthermore, the temporal artery biopsy is occasionally positive despite a normal erythrocyte sedimentation rate. Treatment is aimed at relieving the patient's symptoms and normalizing the erythrocyte sedimentation rate. Because of the wide spectrum of clinical and laboratory finding in temporal arteritis, no one specific treatment regimen with systemic corticosteroids works for all patients. Temporal arteritis is a well known disease of the elderly which ir rarely fatal but results in significant visual morbidity (Hinzpeter & Naumann, 1976; Spencer & Hoyt, 1960). Since Hutchinson's (1890) description, more than a thousand articles have been written on the subject (Cohen & Smith, 1974). Despite this, many unanswered questions and controversies remain concerning the diagnosis, prognosis and treatment of temporal arteritis. My goal is to review these questions and areas of controversy.

show abstract

Section: Juvenile Temporal Arteritismentioning

confidence: 99%

Controversies regarding Giant cell (Temporal, Cranial) arteritis

Eshaghian

1979

Doc Ophthalmol

View full text Add to dashboard Cite

show abstract

“…A detailed study of the anatomic relations of the median nerve within the carpal tunnel was reported (1042). The carpal tunnel syndrome was noted to result from acute thrombosis of a persistent median artery (169,179) and from rubella tenosynovitis at the wrist (215).…”

Section: Carpal Tunnel Syndromementioning

confidence: 99%