Giant cell reparative granuloma of the hallux following enchondroma

Kamoun, Khaled; Sellami, Tarak; Jlailia, Zied; Abid, Layla; Jenzri, Mourad; Bouaziz, Mouna Chelli; Zouar, Omar

doi:10.11604/pamj.2015.22.363.8309

Cited by 5 publications

(3 citation statements)

References 8 publications

(14 reference statements)

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“…For bone tumors of the talus, currently available treatment methods include partial talus resection[ 6 ] and fusion surgery[ 7 ]. The more widely accepted surgical method is fusion surgery, including talocrural arthrodesis and shortening arthrodesis between the calcaneus and the tibia[ 8 , 9 ].…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional printed talar prosthesis with biological function for giant cell tumor of the talus: A case report and review of the literature

Yang¹,

Mu²,

Xu³

et al. 2021

WJCC

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BACKGROUND Giant cell tumors (GCT) are most commonly seen in the distal femur. These tumors are uncommon in the small bones of the hand and feet, and a very few cases have been reported. A giant cell tumor of the talus is rarely seen clinically and could be a challenge to physicians. CASE SUMMARY We report a rare case of GCT of the talus in one patient who underwent a new reconstructive surgery technique using a three-dimensional (3D) printing talar prosthesis. The prosthesis shape was designed by tomographic image processing and segmentation using technology to match the intact side by mirror symmetry with 3D post-processing technologies. The patient recovered nearly full range of motion of the ankle after 6 mo. The visual analogue scale and American Orthopaedic Foot and Ankle Society scores were 1 and 89 points, respectively. CONCLUSION We demonstrated that 3D printing of a talar prosthesis is a beneficial option for GCT of the talus.

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Section: Introductionmentioning

confidence: 99%

Three-dimensional printed talar prosthesis with biological function for giant cell tumor of the talus: A case report and review of the literature

Yang¹,

Mu²,

Xu³

et al. 2021

WJCC

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“…In the most upto-date WHO classification, these two lesions have been included in the group of giant cell lesions of bone [4]. These lesions are typically found at the facial bones and skull, but have also been reported in decreasing frequency in the small bones of the hands and feet [5][6][7][8][9][10][11][12][13][14][15][16], in the long bones [3,[17][18][19][20][21], and in the vertebrae [3,22]. We present a rare case of GCRG of the scapula treated with surgical resection.…”

Section: Introductionmentioning

confidence: 99%

Giant cell reparative granuloma of the scapula: report of a case and literature review

et al. 2019

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Giant cell reparative granulomas (GCRGs) are non-neoplastic inflammatory lesions, usually observed in the maxilla, mandible or small bones of the hands and feet. These lesions present a wide range of morphology and the misinterpretation with other giant cell lesions can often occur. We report the case of a 47-year-old woman with GCRG in the left scapula, presenting some uncommon features: the location (scapula) and age at presentation, the lack of underlying bone disease such as Paget's disease or fibrous dysplasia, the large aggressive expansile aspect of the lesion. This was a therapeutic study, level IV (case series with no or a historical control group).

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“…Giant-cell tumors (GCTs) of bone are locally aggressive tumors found throughout the skeleton, in long bones,[123] bones of the hand[4] or feet,[5] and in the spine. [6] Central giant-cell granulomas (CGCGs) are locally aggressive oral cavity tumors with histology similar to other giant-cell lesions.…”

Section: Introductionmentioning

confidence: 99%

Denosumab treatment for aggressive multiple recurrent familial central giant-cell granulomas

Rytkönen

Ottavainen

Rytkönen

et al. 2018

Ann Maxillofac Surg

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Background:Aggressive familial giant-cell granulomas of the jaws can be severely deforming. Surgical and nonsurgical treatments may be associated with multiple recurrences. Denosumab, a new generation antiresorptive drug, is an osteoclast inhibitor, which may be particularly useful to manage such potentially disfiguring lesions.Materials and Methods:Two sisters, both with a history of multiple recurrent aggressive central giant-cell granuloma (CGCG)-like lesions in both jaws, were referred for management. All lesions were histologically consistent with the diagnosis of CGCG. The lesions were treated surgically with curettage and perilesional injection of triamcinolone. In particular, the older sister had four separate anatomic sites where some of her lesions had multiple recurrences necessitating three repeat procedures. A course of subcutaneous denosumab was administered following the last giant-cell granuloma removal in both sisters.Results:Bony healing was normal. No further recurrences were observed over 3.5 years of follow-up after denosumab therapy in either sister.Conclusions:In this small cohort comprising two sisters with multiple aggressive recurrent giant-cell granuloma lesions at multiple sites in the mouth, subcutaneous denosumab administration was associated with success over 3.5 years of follow-up. This report cautiously adds to the clinical experience in the use of denosumab for the treatment of recurrent aggressive familial CGCG lesions.

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Giant cell reparative granuloma of the hallux following enchondroma

Cited by 5 publications

References 8 publications

Three-dimensional printed talar prosthesis with biological function for giant cell tumor of the talus: A case report and review of the literature

Three-dimensional printed talar prosthesis with biological function for giant cell tumor of the talus: A case report and review of the literature

Giant cell reparative granuloma of the scapula: report of a case and literature review

Denosumab treatment for aggressive multiple recurrent familial central giant-cell granulomas

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