Giant Cell Tumor (GCT) of Distal Femur with Pathological Fracture - A Case Report

Abstract

Introduction: Giant cell tumor [GCT] is a relatively common, locally aggressive but most often a benign neoplasm that is associated with a large biological spectrum. The GCT accounts for 4-10% of all bone tumors and approximately 20% of all benign bone tumors. Case Report: We have a 35 year old male patient, who presented with right knee pain after a trivial trauma (history slip and fall while walking) and X ray revealed pathological fracture of the medial condyle of femur along with a lytic lesion. On further investigation with other modalities such as CT scan and MRI was suggestive of giant cell tumor in the distal femur confirmed with a biopsy, and the patient was referred to a higher centre for the management of the same with the pathological fracture of the medial condyle of the femur. Conclusion: The diagnosis of giant cell tumor, as seen, is made based on several factors taken into account including history, clinical examination, imaging techniques and finally the confirmatory biopsy of the lesion. This also helps in grading and staging of the tumor which helps in determining the prognosis and deciding the further treatment modalities.