Giant cell tumor of the spine: computed tomography appearance and review of the literature

Bidwell, J K; Young, Jeremy W. R.; Khalluff, Edgar

doi:10.1016/0149-936x(87)90104-4

Cited by 42 publications

(19 citation statements)

References 10 publications

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“…The clinical symptoms are primarily pain (often with a radicular distribution), weakness, and sensory deficits. A dramatic increase in lesion size can occasionally be associated with pregnancy and is presumably related to hormonal stimulation [3]. However, in our series, only one case was detected in the cervical spine.…”

Section: Discussioncontrasting

confidence: 44%

“…Most of these lesions occur in the sacrum, followed in order of decreasing frequency by the thoracic, cervical, and lumbar segments [3]. Spinal lesions are more frequently found in women and affect patients in their second to fourth decades of life [4].…”

Section: Discussionmentioning

confidence: 99%

“…Although the features of giant cell tumors of the appendicular skeleton have been well described in the literature, there are few reports of MRI of vertebral tumors, which are limited to case reports and a few examples included in general reviews of spinal lesions [1][2][3]. In this study, the clinical records and MRI findings of 10 patients with giant cell tumors of the spine were reviewed retrospectively to define the typical MRI features of these unusual lesions.…”

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confidence: 99%

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MRI Findings of Giant Cell Tumors of the Spine

Kwon

Chung

Cho

et al. 2007

American Journal of Roentgenology

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Section: Discussioncontrasting

confidence: 44%

Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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MRI Findings of Giant Cell Tumors of the Spine

Kwon

Chung

Cho

et al. 2007

American Journal of Roentgenology

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“…Most GCTs of the spine occur in the sacrum, followed in order of decreasing frequency by the thoracic, cervical, and lumbar segments with female predominance2). Due to a potentially aggressive behavior, the most important management issue is the prevention of recurrence.…”

Section: Discussionmentioning

confidence: 99%

Giant Cell Tumor of Upper Thoracic Spine

Lee

Kim

et al. 2014

J Korean Neurosurg Soc

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Giant cell tumor (GCT) of the spine is a rare benign tumor, but can be aggressive and can exhibit a high local recurrence rate. Furthermore, GCT of the upper thoracic spine may pose diagnostic and management difficulties. Here, we report a rare case of GCT of the upper thoracic spine with soft tissue extension to the spinal canal. The patient was managed by decompressive laminectomy and posterolateral fusion followed by an injection of polymethylmethacrylate into the vertebral lesion. The patient recovered clinically and showed radiological improvement after surgical treatment without tumor recurrence at his last follow-up of postoperative 7 years. We present this unusual case of GCT and include a review of the literature.

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“…GCTs of the spine develop in skeletally mature patients during the second to fourth decades of life, and they are more frequently seen in females (4,8). A GCT of the spine can present with pain (often with a radicular distribution), weakness and sensory deficits (9,10).…”

Section: Discussionmentioning

confidence: 99%

Vertebra Plana Caused by a Giant Cell Tumor: A Case Report and Literature Review

Gyu

Shin

Park

et al. 2010

J Korean Soc Radiol

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Vertebra plana is a radiologic diagnosis that indicates complete compression of the vertebral body (1). Although eosinophilic granuloma of the bone is the most frequent benign disease responsible for vertebra plana (2), it can be caused by several pathological conditions. Vertebral plana caused by a giant cell tumor (GCT) has been mentioned in only a few case reports in the English medical literature, and those case reports were without a detailed description (1). To the best of our knowledge, the computed tomography (CT) and magnetic resonance (MR) imaging features of GCT presenting as vertebra plana have seldom been reported in the radiological literature. We report here on the case of

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Giant cell tumor of the spine: computed tomography appearance and review of the literature

Cited by 42 publications

References 10 publications

MRI Findings of Giant Cell Tumors of the Spine

MRI Findings of Giant Cell Tumors of the Spine

Giant Cell Tumor of Upper Thoracic Spine

Vertebra Plana Caused by a Giant Cell Tumor: A Case Report and Literature Review

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