Giant cell tumor of the spine: A review of 9 surgical interventions in 6 cases

Bhojraj, Shekhar Y; Nene, Abhay; Mohite, Shubha N; Varma, Raghuprasad

doi:10.4103/0019-5413.32047

Cited by 18 publications

(3 citation statements)

References 11 publications

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“…Middle age and slight male preponderance has been reported. Common symptoms include [12,13] :  Back pain.  Neurological deficit due to spinal cord compression.…”

Section: Discussionmentioning

confidence: 99%

Giant cell tumor of dorsal spine: A rare case report

Ghongade¹,

Chikhale²,

Pundkar³

et al. 2022

Int. J. Case Rep. Orthop.

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Giant cell tumor is a relatively rare neoplasm. In GCT the axial skeleton is extremely rarely involved. Most GCT arises in the meta-epiphyseal ends of the long bones. Peak incidence is between 30 to 40 years of age. GCT is usually classified as benign, but shows aggressive behavior and occasionally undergo transformation to malignancy. The patients with GCT in the spine often complain of the lower back pains, as the tumors primarily involve the sacrum. We report a case of an adolescent female complaining of the upper back pain with a sudden weakness of the lower extremities, later diagnosed with the GCT of the D8 vertebra. The present patient was operated using posterior lateral approach of spine and proper rehabilitation was done. Subsequent follow up revealed improvement in carrying out her daily activities.

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“…Middle age and slight male preponderance has been reported. Common symptoms include [12,13] :  Back pain.  Neurological deficit due to spinal cord compression.…”

Section: Discussionmentioning

confidence: 99%

Giant cell tumor of dorsal spine: A rare case report

Ghongade¹,

Chikhale²,

Pundkar³

et al. 2022

Int. J. Case Rep. Orthop.

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“…GCTs may occur in the vertebrae above the sacrum and in the sacrum (2.9 vs. 2.5%, respectively) ( 21 ). Spinal lesions often involve the body of the vertebra, and patients with GCTs of the spine usually present with pain ( 22 , 23 ). A subset of these patients may also report radiculopathic symptoms, varying degrees of myelopathy or other neurological symptoms, due to the compression of the spinal cord ( 1 ).…”

Section: Discussionmentioning

confidence: 99%

Obstructive hydrocephalus as a result of giant cell tumor of the thoracic spine: A case report

et al. 2015

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Giant cell tumors (GCTs) are rare bone tumors that account for ~5% of all primary bone tumors. When GCTs occur in the spine, patients usually present with localized pain and neurological symptoms, such as radiating pain or hyperesthesia. In the current report, an unusual case of a GCT of the thoracic spine associated with hydrocephalus is described. A 48-year-old male presented with urinary retention, loss of sensation in the lower limbs and inability to walk. The patient eventually developed hydrocephalus combined with altered consciousness, indicated by an inability to follow simple commands. Magnetic resonance (MR) imaging demonstrated the presence of a soft tissue mass at the T2 level, and biopsy examination of the tissue confirmed that it was a GCT. The patient experienced a sudden loss of consciousness due to an acute episode of obstructive hydrocephalus. A ventriculoperitoneal shunting procedure was performed to treat the hydrocephalus, and the patient regained normal consciousness, although the paraplegia persisted. An MR examination performed 30 months following surgery demonstrated that the tumor size was stable, consistent with the slow growth that is characteristic of GCTs. Diagnosis of GCTs may be challenging, and relies on radiographic and histopathologic findings. Although rare, acute hydrocephalus as a result of GCTs should not be excluded from a differential diagnosis.

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“…Cement and metallic cages are used for reconstruction because using bone graft may result in recurrence within the graft or delayed/inadequate incorporation of the graft due to radiotherapy. [ 11 ] Baseline immediate postoperative CT/MRI is followed by imaging every 4 months for 2 years and thereafter every 6 months for 5 years.…”

Section: Tumor Recurrence and Radiation Necrosismentioning

confidence: 99%

Complications exclusive to long strut grafts used following multilevel cervical corpectomy: Utilization of advanced imaging techniques

Thippeswamy

Kumaran

Hegde

et al. 2017

Indian Journal of Radiology and Imaging

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When surgical decompression of cervical spine is considered, multilevel cervical corpectomy with long strut grafts is the preferred treatment. This procedure is used in a variety of pathologies including degenerative disease, tumors, trauma and infection. Corpectomy with interbody grafting helps in adequate spinal canal and neural decompression compared to multilevel discectomy, which could be difficult as well as inadequate. Fibular/iliac strut grafts are used for reconstruction along with a stabilizing hardware in this procedure. So far, complete imaging spectrum of complications exclusive to strut graft has not been reported in the literature. This pictorial essay presents complications exclusive to the strut graft, utility of advanced imaging in diagnosis and a brief note on the clinical management of complications.

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Giant cell tumor of the spine: A review of 9 surgical interventions in 6 cases

Cited by 18 publications

References 11 publications

Giant cell tumor of dorsal spine: A rare case report

Giant cell tumor of dorsal spine: A rare case report

Obstructive hydrocephalus as a result of giant cell tumor of the thoracic spine: A case report

Complications exclusive to long strut grafts used following multilevel cervical corpectomy: Utilization of advanced imaging techniques

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