Giant Cell Tumor of the Talus: A case report and review of literature

Abstract

Giant cell tumor is described as neoplasm of undifferentiated mesenchymal stromal cells with presence of abundant, multi-nucleated giant cells. It is basically a benign aggressive tumor which involves the epiphyseometaphyseal end of long bones. Giant cell tumor rarely involves small bones of hand and foot, and is a rare finding within the talus. In the case report, a patient complains of pain and swelling over the left ankle for one year. Plain radiographs and computerized tomography scan (CT) and CT guided fine needle aspiration cytology suggested a diagnosis of giant cell tumor. The tumor was of grade І according to Campanacci grading and there was not cortical break. Treatment consisted of intralesional curettage and an autogenous cancellous bone graft. After two years follow-up, the patient was able to walk with full weight bearing on the affected limb without pain. There were no signs of recurrence both clinically or radiographically.

Management of aggressive giant cell tumor of calcaneal bone: A case report

“…Conservative surgery with careful curettage and placement of bone cement should be considered the treatment of choice when feasible [4] . However, aggressive GCTs may require wide excision and reconstruction or may be amputation [1] , [2] . In this case, we performed wide excision, bone and soft tissue reconstructions.…”

“…Fluid-fluid levels, consistent with secondary formation of aneurysmal bone cyst (ABC), are seen in 14% of cases. GCT can mimic or be mimicked by other benign or malignant lesions at both radiologic evaluation and histologic analysis [1] , [2] . Most GCTs occur in the long bones of the lower extremity especially around the knee [1] , [3] .…”

“…GCT can mimic or be mimicked by other benign or malignant lesions at both radiologic evaluation and histologic analysis [1] , [2] . Most GCTs occur in the long bones of the lower extremity especially around the knee [1] , [3] . The bones of the feet are considered atypical locations which is extremely rare and tumor diagnosis in these circumstances is often confusing [2] , [3] .…”

“…However, the recurrence rates have been relatively high, ranging from 15% to 25% [2] . The trend of treatment in aggressive GCT cases, is heading towards limb salvage and amputation is reserved for recurrences and only rarely done [1] , [2] . In this report, we presented a case of 46-year-old male who was diagnosed with GCT of the right calcaneus Campanacci 3 with secondary aneurysmal bone cyst and was treated in our center by wide excision, bony reconstruction using femoral head allograft and sural flap.…”

Aggressive Giant Cell Tumour of Talus with Pulmonary Metastasis-A Rare Presentation

“…Fresh frozen osteochondral allograft reconstruction has also been described for an aggressive GCT of talus but there is paucity of literature on this particular modality of treatment [11]. In judiciously selected cases of giant cell tumour of the talus with the lesion well localized without a cortical break, properly performed extensive curettage and bone grafting can be a good option for complete removal of the tumour while preserving near normal structure and function of the ankle [12].…”