Giant-cell tumor of the middle cranial fossa

Findlay, John M.; Chiasson, David A.; Hudson, Alan R.; Chui, M

doi:10.3171/jns.1987.66.6.0924

Cited by 58 publications

(61 citation statements)

References 29 publications

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“…A giant cell tumor presenting as a mass occupying the middle fossa are extremely rare, and only two instances have been described up to date. 13 These tumors are as a rule extradural and do not invade the intradural compartment. However, two of the cases reported in the literature,13'14 one of which was located in the middle fossa as the present case,'3 showed a pattern of dural invasion and a tendency to infiltrate the brain parenchyma, a finding that was observed also in our patient.…”

Section: Discussionmentioning

confidence: 99%

Giant Cell Tumor (Osteoclastoma) of the Petrous Bone: Case Report

Spallone¹,

Flores²,

Zaldivar³

et al. 1999

Skull Base

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Giant cell tumors, or osteoclastoma, are uncommon bone neoplasms, rarely involving the craniofacial skeleton.1-3 Actually no more than 60 cases of cranial giant cell tumors have been described in the literature.3-We encountered a case of basal middle fossa osteoclastoma occurring in a young adult. The rarity of the lesion, its atypical computed tomography (CT) appearance, and the problems related to its management, prompted the present report. CASE REPORTA 46-year-old Caucasian, right-handed man was admitted in May, 1996, with a chief complaint of progressively decreasing hearing on the right of 8 months duration. At admission the neurological examination was within normal limits except for a 90% right conductive hearing loss. Plane skull X rays were normal. CT scan examination showed a large (5 cm diameter), hypodense lesion, which showed a high enhancement along the peripheral portion following injection of contrast medium (Fig. IA and iB). The mass occupied the right middle fossa and showed intimate relationships with the petrous bone, which, however, did not appear to be eroded (Fig. IC).The mass was approached using a basal subtemporal transzygomatic approach. The upper branch of the facial nerve was spared by performing a subgaleal-subfascial dissection of the soft tissues, as described in a previous paper.7 The mass was mainly extradural, but invaded the basal temporal dura and infiltrated the brain parenchyma. The intradural portion of the lesion was removed by ultrasonic aspirator until the surface of the petrous pyramid was exposed. This appeared to be quite abnormal, and was carefully drilled in the attempt to achieve gross total removal of the lesion. However, due to the lack of reliable landmark for safely conducting bone dissection in the direction of the carotid artery and the facial nerve, drilling was stopped as soon as the bone appeared to be grossly normal. Moreover, we 155 Skull Base Surgery, Volume 9, Number

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Section: Discussionmentioning

confidence: 99%

Giant Cell Tumor (Osteoclastoma) of the Petrous Bone: Case Report

Spallone¹,

Flores²,

Zaldivar³

et al. 1999

Skull Base

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“…Patients with GCTs at TMJ are presented with progressive pain and swelling. Due to compression or local invasion, hearing impairment, facial nerve paralysis, headache, visual area defects, double vision, visual loss, tinnitus, otalgia, vertigo and trismus can occur [64]. Discomforts as jaw locking, mandibular deviation and clicking can also be seen.…”

Section: Giant Cell Tumormentioning

confidence: 99%

Benign Tumors of Temporomandibular Joint

Yurttutan¹,

Öncül²,

AlpayKarasu³

2018

Temporomandibular Joint Pathology - Current Approaches and Understanding

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The temporomandibular joint (TMJ) forms a complex functional system with teeth, bones, connected muscles and ligaments. Any discomfort in any of these structures directly affects the joint. The complaints are mostly pain, malocclusion and swelling.Temporomandibular joint tumors are very uncommon but show symptoms similar to intra-articular disorders that make up most of these disorders. The most common TMJspecific benign tumors are classified after a brief literature review. Our classification also includes the osteoma of the TMJ, other than World Health Organization's (WHO) classification of soft tissue and bone tumors. This benign tumor was also included in the classification because of its higher frequency in the literature. The treatment of these neoplasms may be conservative or radical surgery.

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“…6 Giant cell tumors are benign neoplasms that may exhibit locally aggressive behavior. 21 They are more common in females and have a peak incidence during the fourth decade of life. These are relatively rare in the pediatric population.…”

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confidence: 99%

“…22 Giant cell tumors occur rarely in the skull, but when they do, they have a predilection for the sphenoid bone and also for the temporal bone. 21 Clinical symptoms may include pain, swelling, ophthalmoparesis, and trigeminal hypesthesia. 21,22 Imaging reveals a sharply marginated expansile lytic osseous lesion typically without sclerosis.…”

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confidence: 99%

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Sphenoid Masses in Children: Radiologic Differential Diagnosis with Pathologic Correlation

Lui

Dasari²,

Young³

2010

AJNR Am J Neuroradiol

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SUMMARY:Childhood central skull base masses are rare, often difficult to diagnose, and have overlapping imaging findings. In this review, we provide an overview of the epidemiology, clinical findings, and management of pediatric sphenoid bone and sphenoid sinus masses with an emphasis on imaging findings that may help to differentiate lesions. Radiologic-pathologic correlation is provided. Finally, an imaging-based algorithm is presented as a guide to help radiologists narrow their differential diagnoses. Some of the entities discussed are virtually unique to the pediatric population; others occur rarely in this age group but should be considered in the appropriate clinical setting. Entities included in the discussion are grouped into 2 categories: those that cause nonaggressive osseous remodeling and those that are more commonly associated with aggressive bone changes. Mucocele, aneurysmal bone cyst, giant cell lesions, meningioma, and fibrous dysplasia tend to remodel bone, while entities such as chordoma, craniopharyngioma, rhabdomyosarcoma, sinonasal carcinoma, and neuroblastoma may cause more aggressive local bone changes.ABBREVIATIONS: FLAIR ϭ fluid-attenuated inversion recovery: HE ϭ hematoxylin-eosin; NF 1 ϭ neurofibromatosis type 1; NF 2 ϭ neurofibromatosis type 2; T1WI ϭ T1 weighted imaging; T2WI ϭ T2 weighted imaging

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Giant-cell tumor of the middle cranial fossa

Abstract: The authors report the case of a 23-year-old man with a giant-cell tumor of the right middle cranial fossa floor. His presentation and management are described, and some aspects of this rare neoplasm of the skull base are reviewed. The role of adjuvant radiotherapy is discussed.

Cited by 58 publications

References 29 publications

Giant Cell Tumor (Osteoclastoma) of the Petrous Bone: Case Report

Giant Cell Tumor (Osteoclastoma) of the Petrous Bone: Case Report

Benign Tumors of Temporomandibular Joint

Sphenoid Masses in Children: Radiologic Differential Diagnosis with Pathologic Correlation

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