2012
DOI: 10.1136/bcr.01.2012.5703
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Giant cell tumour of peroneus brevis tendon sheath - a case report and review of literature

Abstract: Giant cell tumour of tendon sheath is a benign soft tissue lesion most commonly found in the flexor aspect of hand and wrist. Being rare in foot and ankle, the unusual presentation of this lesion may sometimes mimic other lesions like lipoma, synovial sarcoma, malignant fibrous histiocytoma, synovial cyst and ganglion. Hence it is important to include this lesion in differential diagnoses especially if the lesion is found to be anchored to any of the surrounding tendons. This article describes the unusual occu… Show more

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Cited by 12 publications
(25 citation statements)
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“…Histologically, it is composed of multinucleated giant cells, haemosiderin deposits, and fibroblasts, and typically presents as a slow-growing mass in the third to fifth decade of life. 42 It has a slight female preponderance. At MRI, GCTTS is usually seen as a longitudinally oriented mass in close relation to joints and tendons of the hands and feet.…”
Section: Gcttsmentioning
confidence: 99%
“…Histologically, it is composed of multinucleated giant cells, haemosiderin deposits, and fibroblasts, and typically presents as a slow-growing mass in the third to fifth decade of life. 42 It has a slight female preponderance. At MRI, GCTTS is usually seen as a longitudinally oriented mass in close relation to joints and tendons of the hands and feet.…”
Section: Gcttsmentioning
confidence: 99%
“…GCTTS, also termed tendosynovial giant cell tumor, is a benign, slow-growing solid soft-tissue tumor, with a mild female predilection (4,5). The most common clinical observation is the development of an asymptomatic mass, and additional symptoms, including pain and a limited range of motion in the joints, are suggestive of compression or involvement of structures adjacent to the tumor (3,4).…”
Section: Discussionmentioning
confidence: 99%
“…The most common clinical observation is the development of an asymptomatic mass, and additional symptoms, including pain and a limited range of motion in the joints, are suggestive of compression or involvement of structures adjacent to the tumor (3,4). The origins of GCTTS remain to be elucidated, including whether the tumor is neoplastic or reactive.…”
Section: Discussionmentioning
confidence: 99%
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“…In contrast it is much rarer in the foot, with only 3-10% of GCT-TS being described in the foot 3 , and is reported to make up 0.8% of foot and ankle masses. 13 There is debate as to whether the tumor is a true neoplasm or a pseudo-neoplastic inflammatory response to soft-tissue trauma 4 . This lesion arises from the synovium of the tendon sheath or synovial lining of joints or bursa and is characterized microscopically by synovial cells, histiocytes, multinucleated giant cells, inflammatory cells, macrophages, xanthoma cells, and collagen 1,2 .…”
Section: Introductionmentioning
confidence: 99%