Giant Congenital Melanocytic Nevi in a Pakistani Newborn

Abstract

Congenital melanocytic nevi arise from overgrowth or disrupted migration of melanocyte precursor in the neural crest. They are also known as coat-sleeve, stocking, bathing trunk or garment nevi. The colour ranges from brown to black, with the lesions presenting as flat to raised nevi. Lesions presenting at birth with a diameter greater than 20cm are labelled giant congenital melanocytic nevi. Risk increases with an increase in the number of satellite lesions near the giant nevus. Management includes regular clinical follow-up monitoring of changes in the lesion and surgical procedures in cases with risk of melanoma and psychological support. The purpose of this case presentation is to describe a rare issue of giant congenital melanocytic nevi in a newborn, along with a literature review and discussion on possible management options.

Giant congenital melanocytic nevus in an Afghan child

“…Congenital melanocytic nevi (CMN) are cutaneous lesions characterized histologically by benign proliferations of melanocytes. 1 GCMN in compare to CMN are deeper and extend more profound with irregular in margin, dark colored, and covered with coarse hair. 2 Neurocutaneous melanoma is associated with GCMN which indicated bad prognosis of the disease.…”