Giant Ileocecal Inflammatory Fibroid Polyp: Unique Clinical Presentation

Abstract

Inflammatory fibroid polyps (IFPs) are infrequent gastrointestinal tract benign neoplasms. They mostly occur in the stomach especially the antrum. Signs and symptoms depend on their anatomic location and lesion size. Lesion biopsies are very challenging for accurate diagnosis in these lesions. Histopathological examination of resected tissue along with immunohistochemical studies is the perfect way to confirm the final diagnosis. In this paper, the authors present an unusual case of IFP in a 23-year-old female patient presented to the emergency room (ER) with a picture of intestinal obstruction and severe abdominal pain. Her investigations revealed a huge mass located at the ileocecal valve, with overall features mimic gastrointestinal stromal tumor (GIST) clinical presentation. Surgical resection is considered the most commonly used treatment method. The overall prognosis is good with a low risk of recurrence.

Mesenchymal Tumors of the Gastrointestinal Tract—Beyond GIST—A Review

“…The tumors vary in gross size; most are usually less than 3 cm, but in some cases they can be up to 7 cm [52].…”

“…The tumors vary in gross size; most are usually less than 3 cm, but in some cases th can be up to 7 cm [52] Histological morphology is typical. The lesion is usually centered in the submuco and composed of a proliferation of spindle and stellate cells in a haphazard distributi The stroma is vaguely myxoid and contains inflammatory cells, namely eosinophils.…”