Giant lipoblastoma of the thigh: A rare soft tissue tumor in an infant

Abstract

Lipoblastoma is a rare lipomatous tumor encountered almost exclusively in infants and young children. It arises from embryonic white fat. The common site of involvement is the extremities. In spite of their potential for local invasion, they are benign tumors. We report a case of a lipoblastoma in an infant and review the literature pertaining to clinical management of these tumors.

Lipoblastoma in an 8-year-old child: An atypical presentation of a rare tumor

“…Clinically, the differential diagnosis will be with lipoma, lymphangioma or myxoid liposarcoma. [1] Imaging tests are very important and the best technique is MRI, [4] which will usually show an encapsulated tumor with cystic areas and high-intensity signals on both T1-weighted and T2weighted images. [5] The treatment of choice is surgical; but if a complete surgical approach is not possible, damaging adjacent structures is not justified, as …”

“…Although, extremely rare, there have been cases reported in adults. [3] They are most common in the extremities, [4] occurring in 61% of the cases. Only 11% occur in the head and neck, [4] as in the case of our patient.…”

“…[3] They are most common in the extremities, [4] occurring in 61% of the cases. Only 11% occur in the head and neck, [4] as in the case of our patient. Clinically, the differential diagnosis will be with lipoma, lymphangioma or myxoid liposarcoma.…”

Giant gluteal lipoblastoma associated with hepatic haemangioma and bilateral nephromegaly

“…She has been followed with serial ultrasound scans and the hepatic haemangioma slowly regressed and spontaneously resolved at 21 months, nephromegaly resolved to 50th centile at the age of 4 years and there is no tumour recurrence at 6 years follow-up. Lipoblastoma is a rare benign lipomatous tumour arising from embryonic white fat and encountered almost exclusively in infants and young children 1. Surgical excision is the treatment of choice but spontaneous resolution has been reported 2.…”

A giant popliteal lipoblastoma in a 23-month-old girl: a case report

“…Lipoblastomas (LBSs) are rare benign tumors, accounting for less than 1% of childhood neoplasms [ 1 ]. They arise from embryonic white fat and almost always occur in babies and children (approximately 80% before 3 years of age and 40% before 1 year of age) [ 2 ].…”