Giant Liver Hemangioma Mimicking a Hydronephrotic Kidney on 99mTc-DTPA Scintigraphy

Abstract

We report a case of a 56-year-old woman who underwent 99mTc-DTPA renal scintigraphy for the evaluation of a right pelviureteric junction calculi, which incidentally showed radiotracer uptake in a giant liver hemangioma. The initial scintigraphic images showed a large lobulated lesion with peripheral uptake of radiotracer at the right abdominal region, resembling a large hydronephrotic kidney. However, the pattern of progression of the radiotracer, coupled with the clinical history and available corresponding radiologic images, confirmed the uptake to be that of a giant liver hemangioma.

Incidental Detection of Ilium Langerhans Cell Histiocytosis on 99mTc-DTPA Renal Dynamic Scintigraphy

“…Abnormally extrarenal elevated DTPA uptake can be occasionally seen on renal scintigraphy. [1][2][3][4][5][6][7][8][9][10][11][12] Neoplastic disease is the most common etiologies. Abnormal DTPA uptake in skeletal diseases could be due to bone marrow biopsy, 2 lumbar tuberculosis, 4 bone metastases, 10-12 chordoma, 13 Paget disease, 14 and Ewing sarcoma.…”

“…The findings were consistent with the diagnosis of LCH. Abnormally extrarenal elevated DTPA uptake can be occasionally seen on renal scintigraphy [1][2][3][4][5][6][7][8][9][10][11][12]. Neoplastic disease is the most common etiologies.…”

Uptake of 99mTc-DTPA in Bone Metastases From Follicular Thyroid Carcinoma

“…Many case reports have described increased activity of 99m Tc-DTPA in various pathologies. These include urinoma, 1 giant liver hemangioma, 2 lumbar tuberculosis, 3 Langerhans cell histiocytosis, 4 adrenal pheochromocytoma, 5 retroperitoneal liposarcoma, 6 and retroperitoneal malignant peripheral nerve sheath tumor 7 . In addition, the skeletal metastases from poorly differentiated neuroendocrine tumors, 8 pancreatic adenocarcinoma, 9 and renal clear cell carcinoma 10 can also present with such pattern on 99m Tc-DTPA renography.…”